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10.1016/j.jconrel.2015.10.009 http://scihub22266oqcxt.onion/10.1016/j.jconrel.2015.10.009 C4668934!4668934!26453806     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Control+Release 2015 ; 219 (ä): 181-91 Nephropedia Template TP {{tp|p=26453806|t=2015. Polymeric oncolytic adenovirus for cancer gene therapy |pdf=|usr=}}{{26453806}} gab.com Text Polymeric oncolytic adenovirus for cancer gene therapy JO: J Control Release http://www.kidney.de/pget.php?&tw=1&pmid=26453806 #FOAvip Oncolytic adenovirus (Ad) vectors present a promising modality to treat cancer. Many clinical trials have been done with either naked oncolytic Ad or combination with chemotherapies. However, the systemic injection of oncolytic Ad in clinical applications is restricted due to significant liver toxicity and immunogenicity. To overcome these issues, Ad has been engineered physically or chemically with numerous polymers for shielding the Ad surface, accomplishing extended blood circulation time and reduced immunogenicity as well as hepatotoxicity. In this review, we describe and classify the characteristics of polymer modified oncolytic Ad following each strategy for cancer treatment. Furthermore, this review concludes with the highlights of various polymer-coated Ads and their prospects, and directions for future research. Twit Text FOAVip Polymeric oncolytic adenovirus for cancer gene therapy ????J Control Release http://www.kidney.de/pget.php?&tw=1&pmid=26453806 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26453806 #FOAvip English Wikipedia <ref>{{Cite pmid|26453806}}</ref> Polymeric oncolytic adenovirus for cancer gene therapy #MMPMID26453806 Choi JW; Lee YS; Yun CO; Kim SW J Control Release 2015[Dec]; 219 (ä): 181-91 PMID26453806show ga Oncolytic adenovirus (Ad) vectors present a promising modality to treat cancer. Many clinical trials have been done with either naked oncolytic Ad or combination with chemotherapies. However, the systemic injection of oncolytic Ad in clinical applications is restricted due to significant liver toxicity and immunogenicity. To overcome these issues, Ad has been engineered physically or chemically with numerous polymers for shielding the Ad surface, accomplishing extended blood circulation time and reduced immunogenicity as well as hepatotoxicity. In this review, we describe and classify the characteristics of polymer modified oncolytic Ad following each strategy for cancer treatment. Furthermore, this review concludes with the highlights of various polymer-coated Ads and their prospects, and directions for future research. äPolymeric oncolytic adenovirus for cancer gene therapy (epmc).pdf DeepDyve Pubget Overpricing