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2015 ; 68
(6
): 586-93
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Clinical and psychological characteristics of propofol abusers in Korea: a survey
of propofol abuse in 38, non-healthcare professionals
#MMPMID26634083
Kim EJ
; Kim SH
; Hyun YJ
; Noh YK
; Jung HS
; Han SY
; Park CH
; Choi BM
; Noh GJ
Korean J Anesthesiol
2015[Dec]; 68
(6
): 586-93
PMID26634083
show ga
BACKGROUND: The aim of this study is to investigate the characteristics of
propofol abuse based on the results of a survey analysis of abusers among
non-healthcare professionals in Korea. METHODS: Thirty-eight propofol abusers
were questioned between October and December 2010, and were enrolled and
voluntarily participated in a structured survey consisting of an interview and
completing a previously prepared questionnaire. The questionnaire was divided
into three distinct parts: part 1 dealt with the history of propofol abuse; part
2 highlighted the problems caused by propofol abuse; and part 3 enquired
regarding demographics of abusers. RESULTS: Thirty-one (81.6%) of the 38
interviewees abused propofol for more than one year. During the last 12 months,
34 (89.0%) received propofol at two or three times a week. The minimum and
maximum amounts of propofol (median, range) administered each time were 500 (100,
1000) and 2000 (500, 4000) mg, respectively. Stress relief and the maintenance of
a sense of well-being were quoted the most important reasons for the first-time
administration of propofol and its subsequent abuse, respectively. The majority
of abusers (36.0, 97.3%) reported a sense of pleasure or euphoria at the time of
their propofol injection. Withdrawal symptoms occurred in five abusers (13.2%).
Thirteen (36.1%) reported disruptions in their work life. None of the respondents
had previously admitted to and or reported abuse of any other controlled
substances. CONCLUSIONS: These results provided reference data for the regulation
of propofol in Korea as a controlled substance and may also be of interest to
international agencies in other countries.