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10.1038/nmeth.3616

http://scihub22266oqcxt.onion/10.1038/nmeth.3616
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C4666809!4666809!26436482
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suck abstract from ncbi


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pmid26436482      Nat+Methods 2015 ; 12 (12): 1132-4
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  • Noncontact three-dimensional mapping of intracellular hydro-mechanical properties by Brillouin microscopy #MMPMID26436482
  • Scarcelli G; Polacheck WJ; Nia HT; Patel K; Grodzinsky AJ; Kamm RD; Yun SH
  • Nat Methods 2015[Dec]; 12 (12): 1132-4 PMID26436482show ga
  • Current measurements of the biomechanical properties of cells require physical contact with cells or lack sub-cellular resolution. Here, we developed a label-free optical microscopy technique based on Brillouin light scattering capable of measuring intracellular longitudinal modulus with optical resolution. We obtained 3D Brillouin maps of cells in 2D and 3D microenvironments, which reveal mechanical changes due to cytoskeletal modulation and cell volume regulation.
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