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Quality and Outcomes of Treatment of Hypercalcemia of Malignancy #MMPMID26068056
Cancer Invest 2015[Sep]; 33 (8): 331-9 PMID26068056show ga
Using a nationwisde database, 4874 patients with hypercalcemia of malignancy were identified. The in-hospital mortality rate was 6.8%. Overall, 1971 (40.4%) patients received pamidronate and 1399 (28.7%) received zoledronic acid during hospitalization. Calcitonin was utilized in 1337 (27.4%) patients while glucocorticoids were administered to 1311 (26.9%). Use of contraindicated medications was noted in 136 (2.8%) patients who received thiazide diuretics and 12 (0.2%) who received lithium. Tumor site, presence of bone metastases, and severity of illness were predictors of treatment. There was no association between treatment with bisphosphonates, calcitonin, or glucocorticoids and morbidity or mortality.