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10.1107/S2053230X15019986

http://scihub22266oqcxt.onion/10.1107/S2053230X15019986
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C4666478!4666478!26625292
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suck abstract from ncbi


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pmid26625292      Acta+Crystallogr+F+Struct+Biol+Commun 2015 ; 71 (Pt 12): 1498-510
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  • Seeding for sirtuins: microseed matrix seeding to obtain crystals of human Sirt3 and Sirt2 suitable for soaking #MMPMID26625292
  • Rumpf T; Gerhardt S; Einsle O; Jung M
  • Acta Crystallogr F Struct Biol Commun 2015[Dec]; 71 (Pt 12): 1498-510 PMID26625292show ga
  • In the present study, microseed matrix seeding was successfully applied to obtain a large number of crystals of the human sirtuin isotypes Sirt2 and Sirt3. These crystals appeared predictably in diverse crystallization conditions, diffracted to a higher resolution than reported in the literature and were subsequently used to study the protein?ligand interactions of two indole inhibitors.
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