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10.14797/mdcj-11-3-176 http://scihub22266oqcxt.onion/10.14797/mdcj-11-3-176 C4666425!4666425!26634026     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Methodist+Debakey+Cardiovasc+J 2015 ; 11 (3): 176-80 Nephropedia Template TP {{tp|p=26634026|t=2015. Therapeutic Transdifferentiation: A Novel Approach for Ischemic Syndromes |pdf=|usr=}}{{26634026}} gab.com Text Therapeutic Transdifferentiation: A Novel Approach for Ischemic Syndromes JO: Methodist Debakey Cardiovasc J http://www.kidney.de/pget.php?&tw=1&pmid=26634026 #FOAvip The technological development of induced pluripotent stem cells (iPSCs) has overcome many of the limitations of adult and embryonic stem cells. We have found that activation of innate immunity signaling is necessary for this process, as it facilitates epigenetic plasticity in cells by a process called transflammation. More recently, we have discovered that transflammation also facilitates the transdifferentiation of cells directly from one somatic cell type to another. This insight may lead to a promising therapeutic pathway that avoids reverting cells all the way back to pluripotency before achieving a cell type of interest. While there is much therapeutic promise to transflammation and transdifferentiation, there is also evidence that transdifferentiation plays a role in some pathological conditions, including atherosclerosis. Ultimately, better understanding of transflammation will facilitate the development of regenerative therapies. Twit Text FOAVip Therapeutic Transdifferentiation: A Novel Approach for Ischemic Syndromes ????Methodist Debakey Cardiovasc J http://www.kidney.de/pget.php?&tw=1&pmid=26634026 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26634026 #FOAvip English Wikipedia <ref>{{Cite pmid|26634026}}</ref> Therapeutic Transdifferentiation: A Novel Approach for Ischemic Syndromes #MMPMID26634026 Connell JP; Kodali S; Cooke JP Methodist Debakey Cardiovasc J 2015[Jul]; 11 (3): 176-80 PMID26634026show ga The technological development of induced pluripotent stem cells (iPSCs) has overcome many of the limitations of adult and embryonic stem cells. We have found that activation of innate immunity signaling is necessary for this process, as it facilitates epigenetic plasticity in cells by a process called transflammation. More recently, we have discovered that transflammation also facilitates the transdifferentiation of cells directly from one somatic cell type to another. This insight may lead to a promising therapeutic pathway that avoids reverting cells all the way back to pluripotency before achieving a cell type of interest. While there is much therapeutic promise to transflammation and transdifferentiation, there is also evidence that transdifferentiation plays a role in some pathological conditions, including atherosclerosis. Ultimately, better understanding of transflammation will facilitate the development of regenerative therapies. äTherapeutic Transdifferentiation: A Novel Approach for Ischemic Syndro(epmc).pdf DeepDyve Pubget Overpricing