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10.1186/s40248-015-0031-2 http://scihub22266oqcxt.onion/10.1186/s40248-015-0031-2 C4666040!4666040!26629341     free     free     free       Multidiscip+Respir+Med 2015 ; 10 (ä): ä Nephropedia Template TP {{tp|p=26629341|t=2015. The role of iron in pulmonary pathology |pdf=|usr=}}{{26629341}} gab.com Text The role of iron in pulmonary pathology JO: Multidiscip Respir Med http://www.kidney.de/pget.php?&tw=1&pmid=26629341 #FOAvip Respiratory disease accounts for a large proportion of emergency admissions to hospital and diseaseassociated mortality. Genetic association studies demonstrate a link between iron metabolism and pulmonary disease phenotypes. IREB2 is a gene that produces iron regulatory protein 2 (IRP2), which has a key role in iron homeostasis. This review addresses pathways involved in iron metabolism, particularly focusing on the role of IREB2. In addition to this, environmental factors also influence phenotypic variation in respiratory disease, for example inhaled iron from cigarette smoke is deposited in the lung and causes tissue damage by altering iron homeostasis. The effects of cigarette smoke are detailed in this article, particularly in relation to lung conditions that favour the upper lobes, such as emphysema and lung cancer. Clinical applications of iron homeostasis are also discussed in this review, especially looking at the pathophysiology of chronic obstructive pulmonary disease, lung cancer, pulmonary infections and acute respiratory distress syndrome. Promising new treatments involving iron are also covered. Twit Text FOAVip The role of iron in pulmonary pathology ????Multidiscip Respir Med http://www.kidney.de/pget.php?&tw=1&pmid=26629341 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26629341 #FOAvip English Wikipedia <ref>{{Cite pmid|26629341}}</ref> The role of iron in pulmonary pathology #MMPMID26629341 Khiroya H; Turner AM Multidiscip Respir Med 2015[]; 10 (ä): ä PMID26629341show ga Respiratory disease accounts for a large proportion of emergency admissions to hospital and diseaseassociated mortality. Genetic association studies demonstrate a link between iron metabolism and pulmonary disease phenotypes. IREB2 is a gene that produces iron regulatory protein 2 (IRP2), which has a key role in iron homeostasis. This review addresses pathways involved in iron metabolism, particularly focusing on the role of IREB2. In addition to this, environmental factors also influence phenotypic variation in respiratory disease, for example inhaled iron from cigarette smoke is deposited in the lung and causes tissue damage by altering iron homeostasis. The effects of cigarette smoke are detailed in this article, particularly in relation to lung conditions that favour the upper lobes, such as emphysema and lung cancer. Clinical applications of iron homeostasis are also discussed in this review, especially looking at the pathophysiology of chronic obstructive pulmonary disease, lung cancer, pulmonary infections and acute respiratory distress syndrome. Promising new treatments involving iron are also covered. äThe role of iron in pulmonary pathology (epmc).pdf DeepDyve Pubget Overpricing