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10.1038/srep17438 http://scihub22266oqcxt.onion/10.1038/srep17438 C4664929!4664929!26621340     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Sci+Rep 2015 ; 5 (ä): ä Nephropedia Template TP {{tp|p=26621340|t=2015. Cardiotrophin-1 is inversely associated with obesity in non-diabetic individuals |pdf=|usr=}}{{26621340}} gab.com Text Cardiotrophin-1 is inversely associated with obesity in non-diabetic individuals JO: Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=26621340 #FOAvip Cardiotrophin-1 is known to be a key regulator of energy homeostasis, as well as glucose and lipid metabolism in vivo. However, there are inconsistent results of the association between cardiotrophin-1 and obesity in humans, possibly confounded by hyperglycemia. Therefore, the aim of this study was to investigate the relationships among cardiotrophin-1 levels, overweight and obese individuals without diabetes in a Chinese population. The median (inter-quarter range) serum cardiotrophin-1 levels were 447.9 (230.9, 913.9), 350.6 (201.1, 666.5), and 288.1 (162.3, 572.4) pg/ml in non-diabetic subjects who were of normal weight (n?=?522), overweight (n?=?203), and obese (n?=?93), respectively (trend test p?<?0.001). Subjects who were overweight and obese had significantly lower cardiotrophin-1 levels than those with normal weight. The multivariate linear regression analyses showed that overweight (beta?=??338.718, 95% CI?=??552.786?~??124.651, p?<?0.01), obese (beta?=??530.275, 95% CI?=??832.967?~??227.583, p?<?0.01), and smoking (beta?=??377.375, 95% CI?=??654.353?~??100.397, p?<?0.01) were negatively related to cardiotrophin-1 after adjusting for age, gender, HOMA-IR, hypertension, total cholesterol, HDL, triglyceride, eGFR, ALT, and alcohol drinking. The results of this study provided epidemiological evidence that non-diabetic subjects who were overweight or obesity had significantly lower cardiotrophin-1 concentrations than those with normal weight, and both obesity and being overweight were inversely associated with cardiotrophin-1 levels. Twit Text FOAVip Cardiotrophin-1 is inversely associated with obesity in non-diabetic individuals ????Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=26621340 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26621340 #FOAvip English Wikipedia <ref>{{Cite pmid|26621340}}</ref> Cardiotrophin-1 is inversely associated with obesity in non-diabetic individuals #MMPMID26621340 Hung HC; Lu FH; Wu HT; Ou HY; Yang YC; Wu JS; Chang CJ Sci Rep 2015[]; 5 (ä): ä PMID26621340show ga Cardiotrophin-1 is known to be a key regulator of energy homeostasis, as well as glucose and lipid metabolism in vivo. However, there are inconsistent results of the association between cardiotrophin-1 and obesity in humans, possibly confounded by hyperglycemia. Therefore, the aim of this study was to investigate the relationships among cardiotrophin-1 levels, overweight and obese individuals without diabetes in a Chinese population. The median (inter-quarter range) serum cardiotrophin-1 levels were 447.9 (230.9, 913.9), 350.6 (201.1, 666.5), and 288.1 (162.3, 572.4) pg/ml in non-diabetic subjects who were of normal weight (n?=?522), overweight (n?=?203), and obese (n?=?93), respectively (trend test p? äCardiotrophin-1 is inversely associated with obesity in non-diabetic i(epmc).pdf DeepDyve Pubget Overpricing