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10.1073/pnas.1517466112

http://scihub22266oqcxt.onion/10.1073/pnas.1517466112
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C4664346!4664346!26575628
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suck abstract from ncbi


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pmid26575628      Proc+Natl+Acad+Sci+U+S+A 2015 ; 112 (47): 14629-34
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  • Fourteen babies born after round spermatid injection into human oocytes #MMPMID26575628
  • Tanaka A; Nagayoshi M; Takemoto Y; Tanaka I; Kusunoki H; Watanabe S; Kuroda K; Takeda S; Ito M; Yanagimachi R
  • Proc Natl Acad Sci U S A 2015[Nov]; 112 (47): 14629-34 PMID26575628show ga
  • Men without spermatozoa or elongating spermatids in their testes have been considered sterile and are advised to consider using a sperm donor. However, these men may have round spermatids. We have been able to accurately identify these cells based on their structural and physical characteristics (verified by karyotyping and FISH). Round spermatid injection was effectively used in our clinic and resulted in the birth of 14 healthy babies. Although the current success rate of round spermatid injection is not very high compared with intracytoplasmic sperm injection, this procedure can be the last resort for men who cannot produce spermatozoa but wish to use their own genetic material to produce offspring.
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