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10.1073/pnas.1516928112 http://scihub22266oqcxt.onion/10.1073/pnas.1516928112 C4664314!4664314!26561583     free     free     free Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 269.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Proc+Natl+Acad+Sci+U+S+A 2015 ; 112 (47): 14635-40 Nephropedia Template TP {{tp|p=26561583|t=2015. Superresolution imaging reveals structurally distinct periodic patterns of chromatin along pachytene chromosomes |pdf=|usr=}}{{26561583}} gab.com Text Superresolution imaging reveals structurally distinct periodic patterns of chromatin along pachytene chromosomes JO: Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=26561583 #FOAvip The structure of the pachytene chromosome is essential to understand how genetic recombination can happen during meiosis. Using single molecule localization microscopy with DNA staining, we show that chromatin is heavily constrained by defined periodic clusters along the synaptonemal complex (SC). Staining of various posttranslational histone modifications further reveals that the pachytene chromosome is associated with three distinct nanoscale compartments. Whereas chromatin associated with active transcription emanates both axially and radially in hair-like loop structures, the chromatin associated with repressed transcription follows periodic clusters close to the central axis of the SC. These findings suggest a model showing how chromatin and epigenetic modification patterns can be incorporated within the SC to shape the pachytene chromosome. Twit Text FOAVip Superresolution imaging reveals structurally distinct periodic patterns of chromatin along pachytene chromosomes ????Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=26561583 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26561583 #FOAvip English Wikipedia <ref>{{Cite pmid|26561583}}</ref> Superresolution imaging reveals structurally distinct periodic patterns of chromatin along pachytene chromosomes #MMPMID26561583 Prakash K; Fournier D; Redl S; Best G; Borsos M; Tiwari VK; Tachibana-Konwalski K; Ketting RF; Parekh SH; Cremer C; Birk UJ Proc Natl Acad Sci U S A 2015[Nov]; 112 (47): 14635-40 PMID26561583show ga The structure of the pachytene chromosome is essential to understand how genetic recombination can happen during meiosis. Using single molecule localization microscopy with DNA staining, we show that chromatin is heavily constrained by defined periodic clusters along the synaptonemal complex (SC). Staining of various posttranslational histone modifications further reveals that the pachytene chromosome is associated with three distinct nanoscale compartments. Whereas chromatin associated with active transcription emanates both axially and radially in hair-like loop structures, the chromatin associated with repressed transcription follows periodic clusters close to the central axis of the SC. These findings suggest a model showing how chromatin and epigenetic modification patterns can be incorporated within the SC to shape the pachytene chromosome. äSuperresolution imaging reveals structurally distinct periodic pattern(epmc).pdf DeepDyve Pubget Overpricing