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10.3390/jcm4111908 http://scihub22266oqcxt.onion/10.3390/jcm4111908 C4663476!4663476!26569322     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Clin+Med 2015 ; 4 (11): 1908-37 Nephropedia Template TP {{tp|p=26569322|t=2015. Renin-Angiotensin-Aldosterone System Blockade in Diabetic Nephropathy Present Evidences |pdf=|usr=}}{{26569322}} gab.com Text Renin-Angiotensin-Aldosterone System Blockade in Diabetic Nephropathy Present Evidences JO: J Clin Med http://www.kidney.de/pget.php?&tw=1&pmid=26569322 #FOAvip Diabetic Kidney Disease (DKD) is the leading cause of chronic kidney disease in developed countries and its prevalence has increased dramatically in the past few decades. These patients are at an increased risk for premature death, cardiovascular disease, and other severe illnesses that result in frequent hospitalizations and increased health-care utilization. Although much progress has been made in slowing the progression of diabetic nephropathy, renal dysfunction and the development of end-stage renal disease remain major concerns in diabetes. Dysregulation of the renin-angiotensin-aldosterone system (RAAS) results in progressive renal damage. RAAS blockade is the cornerstone of treatment of DKD, with proven efficacy in many arenas. The theoretically-attractive option of combining these medications that target different points in the pathway, potentially offering a more complete RAAS blockade, has also been tested in clinical trials, but long-term outcomes were disappointing. This review examines the ?state of play? for RAAS blockade in DKD, dual blockade of various combinations, and a perspective on its benefits and potential risks. Twit Text FOAVip Renin-Angiotensin-Aldosterone System Blockade in Diabetic Nephropathy Present Evidences ????J Clin Med http://www.kidney.de/pget.php?&tw=1&pmid=26569322 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26569322 #FOAvip English Wikipedia <ref>{{Cite pmid|26569322}}</ref> Renin-Angiotensin-Aldosterone System Blockade in Diabetic Nephropathy Present Evidences #MMPMID26569322 Lozano-Maneiro L; Puente-García A J Clin Med 2015[Nov]; 4 (11): 1908-37 PMID26569322show ga Diabetic Kidney Disease (DKD) is the leading cause of chronic kidney disease in developed countries and its prevalence has increased dramatically in the past few decades. These patients are at an increased risk for premature death, cardiovascular disease, and other severe illnesses that result in frequent hospitalizations and increased health-care utilization. Although much progress has been made in slowing the progression of diabetic nephropathy, renal dysfunction and the development of end-stage renal disease remain major concerns in diabetes. Dysregulation of the renin-angiotensin-aldosterone system (RAAS) results in progressive renal damage. RAAS blockade is the cornerstone of treatment of DKD, with proven efficacy in many arenas. The theoretically-attractive option of combining these medications that target different points in the pathway, potentially offering a more complete RAAS blockade, has also been tested in clinical trials, but long-term outcomes were disappointing. This review examines the ?state of play? for RAAS blockade in DKD, dual blockade of various combinations, and a perspective on its benefits and potential risks. äRenin-Angiotensin-Aldosterone System Blockade in Diabetic Nephropathy (epmc).pdf DeepDyve Pubget Overpricing