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2015 ; 51
(17
): 2718-23
Nephropedia Template TP
gab.com Text
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Clinical trial spots for cancer patients by tumour type: The cancer trials
portfolio at clinicaltrials gov
#MMPMID26321010
Prasad V
; Goldstein JA
Eur J Cancer
2015[Nov]; 51
(17
): 2718-23
PMID26321010
show ga
BACKGROUND: Although participation in cancer clinical trials is low, little is
known about the number of available clinical trials, and open spots for patients.
Moreover, it is unclear what the relationship is between clinical trial openings
and the incidence and mortality of cancer subtypes. METHODOLOGY: We identified
the number of phase I, phase II and phase III registered at clinicaltrials.gov by
cancer (tumour) type. All counts were over the preceding 5 years (2008-2013). We
compared these counts against the incidence and prevalence of disease reported by
Surveillance, Epidemiology and End Results (SEER) database for 32 common cancers.
RESULTS: From 2008 to 2013, 3879 phase I trials, 4982 phase II trials and 1379
phase III trials concerning a cancer subtype were registered in
clinicaltrials.gov. These trials had a cumulative proposed recruitment of
203,396, 421,502 and 697,787 patients, respectively. Trial enrollment varied by
tumour type, with both over and under-representation occurring. CONCLUSION:
Opportunities to enroll in clinical trials vary by phase and tumour type.
Oncologists must remain committed to clinical trials.
|Clinical Trials, Phase I as Topic/*statistics & numerical data
[MESH]
|Clinical Trials, Phase II as Topic/*statistics & numerical data
[MESH]
|Clinical Trials, Phase III as Topic/*statistics & numerical data
[MESH]
|Databases, Factual/statistics & numerical data
[MESH]