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10.1155/2015/390161 http://scihub22266oqcxt.onion/10.1155/2015/390161 C4662999!4662999!26648599     free     free     free       Dis+Markers 2015 ; 2015 (ä): ä Nephropedia Template TP {{tp|p=26648599|t=2015. Tissue Specific Promoters in Colorectal Cancer |pdf=|usr=}}{{26648599}} gab.com Text Tissue Specific Promoters in Colorectal Cancer JO: Dis Markers http://www.kidney.de/pget.php?&tw=1&pmid=26648599 #FOAvip Colorectal carcinoma is the third most prevalent cancer in the world. In the most advanced stages, the use of chemotherapy induces a poor response and is usually accompanied by other tissue damage. Significant progress based on suicide gene therapy has demonstrated that it may potentiate the classical cytotoxic effects in colorectal cancer. The inconvenience still rests with the targeting and the specificity efficiency. The main target of gene therapy is to achieve an effective vehicle to hand over therapeutic genes safely into specific cells. One possibility is the use of tumor-specific promoters overexpressed in cancers. They could induce a specific expression of therapeutic genes in a given tumor, increasing their localized activity. Several promoters have been assayed into direct suicide genes to cancer cells. This review discusses the current status of specific tumor-promoters and their great potential in colorectal carcinoma treatment. Twit Text FOAVip Tissue Specific Promoters in Colorectal Cancer ????Dis Markers http://www.kidney.de/pget.php?&tw=1&pmid=26648599 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26648599 #FOAvip English Wikipedia <ref>{{Cite pmid|26648599}}</ref> Tissue Specific Promoters in Colorectal Cancer #MMPMID26648599 Rama AR; Aguilera A; Melguizo C; Caba O; Prados J Dis Markers 2015[]; 2015 (ä): ä PMID26648599show ga Colorectal carcinoma is the third most prevalent cancer in the world. In the most advanced stages, the use of chemotherapy induces a poor response and is usually accompanied by other tissue damage. Significant progress based on suicide gene therapy has demonstrated that it may potentiate the classical cytotoxic effects in colorectal cancer. The inconvenience still rests with the targeting and the specificity efficiency. The main target of gene therapy is to achieve an effective vehicle to hand over therapeutic genes safely into specific cells. One possibility is the use of tumor-specific promoters overexpressed in cancers. They could induce a specific expression of therapeutic genes in a given tumor, increasing their localized activity. Several promoters have been assayed into direct suicide genes to cancer cells. This review discusses the current status of specific tumor-promoters and their great potential in colorectal carcinoma treatment. äTissue Specific Promoters in Colorectal Cancer (epmc).pdf DeepDyve Pubget Overpricing