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10.3390/ijms161126068 http://scihub22266oqcxt.onion/10.3390/ijms161126068 C4661926!4661926!26610477     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Int+J+Mol+Sci 2015 ; 16 (11): 27796-815 Nephropedia Template TP {{tp|p=26610477|t=2015. Molecular, Cellular and Functional Effects of Radiation-Induced Brain Injury: A Review |pdf=|usr=}}{{26610477}} gab.com Text Molecular, Cellular and Functional Effects of Radiation-Induced Brain Injury: A Review JO: Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=26610477 #FOAvip Radiation therapy is the most effective non-surgical treatment of primary brain tumors and metastases. Preclinical studies have provided valuable insights into pathogenesis of radiation-induced injury to the central nervous system. Radiation-induced brain injury can damage neuronal, glial and vascular compartments of the brain and may lead to molecular, cellular and functional changes. Given its central role in memory and adult neurogenesis, the majority of studies have focused on the hippocampus. These findings suggested that hippocampal avoidance in cranial radiotherapy prevents radiation-induced cognitive impairment of patients. However, multiple rodent studies have shown that this problem is more complex. As the radiation-induced cognitive impairment reflects hippocampal and non-hippocampal compartments, it is of critical importance to investigate molecular, cellular and functional modifications in various brain regions as well as their integration at clinically relevant doses and schedules. We here provide a literature overview, including our previously published results, in order to support the translation of preclinical findings to clinical practice, and improve the physical and mental status of patients with brain tumors. Twit Text FOAVip Molecular, Cellular and Functional Effects of Radiation-Induced Brain Injury: A Review ????Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=26610477 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26610477 #FOAvip English Wikipedia <ref>{{Cite pmid|26610477}}</ref> Molecular, Cellular and Functional Effects of Radiation-Induced Brain Injury: A Review #MMPMID26610477 Balentova S; Adamkov M Int J Mol Sci 2015[Nov]; 16 (11): 27796-815 PMID26610477show ga Radiation therapy is the most effective non-surgical treatment of primary brain tumors and metastases. Preclinical studies have provided valuable insights into pathogenesis of radiation-induced injury to the central nervous system. Radiation-induced brain injury can damage neuronal, glial and vascular compartments of the brain and may lead to molecular, cellular and functional changes. Given its central role in memory and adult neurogenesis, the majority of studies have focused on the hippocampus. These findings suggested that hippocampal avoidance in cranial radiotherapy prevents radiation-induced cognitive impairment of patients. However, multiple rodent studies have shown that this problem is more complex. As the radiation-induced cognitive impairment reflects hippocampal and non-hippocampal compartments, it is of critical importance to investigate molecular, cellular and functional modifications in various brain regions as well as their integration at clinically relevant doses and schedules. We here provide a literature overview, including our previously published results, in order to support the translation of preclinical findings to clinical practice, and improve the physical and mental status of patients with brain tumors. äMolecular, Cellular and Functional Effects of Radiation-Induced Brain (epmc).pdf DeepDyve Pubget Overpricing