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10.1038/srep17357 http://scihub22266oqcxt.onion/10.1038/srep17357 C4661569!4661569!26612138     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Sci+Rep 2015 ; 5 (ä): ä Nephropedia Template TP {{tp|p=26612138|t=2015. A novel algorithm for analyzing drug-drug interactions from MEDLINE literature |pdf=|usr=}}{{26612138}} gab.com Text A novel algorithm for analyzing drug-drug interactions from MEDLINE literature JO: Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=26612138 #FOAvip Drug?drug interaction (DDI) is becoming a serious clinical safety issue as the use of multiple medications becomes more common. Searching the MEDLINE database for journal articles related to DDI produces over 330,000 results. It is impossible to read and summarize these references manually. As the volume of biomedical reference in the MEDLINE database continues to expand at a rapid pace, automatic identification of DDIs from literature is becoming increasingly important. In this article, we present a random-sampling-based statistical algorithm to identify possible DDIs and the underlying mechanism from the substances field of MEDLINE records. The substances terms are essentially carriers of compound (including protein) information in a MEDLINE record. Four case studies on warfarin, ibuprofen, furosemide and sertraline implied that our method was able to rank possible DDIs with high accuracy (90.0% for warfarin, 83.3% for ibuprofen, 70.0% for furosemide and 100% for sertraline in the top 10% of a list of compounds ranked by p-value). A social network analysis of substance terms was also performed to construct networks between proteins and drug pairs to elucidate how the two drugs could interact. Twit Text FOAVip A novel algorithm for analyzing drug-drug interactions from MEDLINE literature ????Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=26612138 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26612138 #FOAvip English Wikipedia <ref>{{Cite pmid|26612138}}</ref> A novel algorithm for analyzing drug-drug interactions from MEDLINE literature #MMPMID26612138 Lu Y; Shen D; Pietsch M; Nagar C; Fadli Z; Huang H; Tu YC; Cheng F Sci Rep 2015[]; 5 (ä): ä PMID26612138show ga Drug?drug interaction (DDI) is becoming a serious clinical safety issue as the use of multiple medications becomes more common. Searching the MEDLINE database for journal articles related to DDI produces over 330,000 results. It is impossible to read and summarize these references manually. As the volume of biomedical reference in the MEDLINE database continues to expand at a rapid pace, automatic identification of DDIs from literature is becoming increasingly important. In this article, we present a random-sampling-based statistical algorithm to identify possible DDIs and the underlying mechanism from the substances field of MEDLINE records. The substances terms are essentially carriers of compound (including protein) information in a MEDLINE record. Four case studies on warfarin, ibuprofen, furosemide and sertraline implied that our method was able to rank possible DDIs with high accuracy (90.0% for warfarin, 83.3% for ibuprofen, 70.0% for furosemide and 100% for sertraline in the top 10% of a list of compounds ranked by p-value). A social network analysis of substance terms was also performed to construct networks between proteins and drug pairs to elucidate how the two drugs could interact. äA novel algorithm for analyzing drug-drug interactions from MEDLINE li(epmc).pdf DeepDyve Pubget Overpricing