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10.1074/jbc.M115.678326

http://scihub22266oqcxt.onion/10.1074/jbc.M115.678326
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C4661404!4661404!26472924
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suck abstract from ncbi


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pmid26472924      J+Biol+Chem 2015 ; 290 (48): 28901-14
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  • The Nogo/Nogo Receptor (NgR) Signal Is Involved in Neuroinflammation through the Regulation of Microglial Inflammatory Activation* #MMPMID26472924
  • Fang Y; Yan J; Li C; Zhou X; Yao L; Pang T; Yan M; Zhang L; Mao L; Liao H
  • J Biol Chem 2015[Nov]; 290 (48): 28901-14 PMID26472924show ga
  • Background: NgR is expressed on microglia and regulates cell adhesion and migration behavior.Results: Nogo/NgR signal induced the expression of proinflammatory factors in microglia through NF-?B and STAT3 signal pathways.Conclusion: Nogo peptide could directly take part in CNS inflammatory process by influencing the expression of proinflammatory factors in microglia.Significance: Nogo/NgR signal might be involved in multiple processes in various inflammation-associated CNS diseases.
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