Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 261.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 261.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 261.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 261.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 261.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 261.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 261.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 261.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 261.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 261.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26071951
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Appl+Health+Econ+Health+Policy
2015 ; 13
(6
): 647-59
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Cost-Effectiveness Analysis of High-Efficiency Hemodiafiltration Versus Low-Flux
Hemodialysis Based on the Canadian Arm of the CONTRAST Study
#MMPMID26071951
Lévesque R
; Marcelli D
; Cardinal H
; Caron ML
; Grooteman MP
; Bots ML
; Blankestijn PJ
; Nubé MJ
; Grassmann A
; Canaud B
; Gandjour A
Appl Health Econ Health Policy
2015[Dec]; 13
(6
): 647-59
PMID26071951
show ga
AIM: The aim of this study was to assess the cost effectiveness of
high-efficiency on-line hemodiafiltration (OL-HDF) compared with low-flux
hemodialysis (LF-HD) for patients with end-stage renal disease (ESRD) based on
the Canadian (Centre Hospitalier de l'Université de Montréal) arm of a
parallel-group randomized controlled trial (RCT), the CONvective TRAnsport STudy.
METHODS: An economic evaluation was conducted for the period of the RCT (74
months). In addition, a Markov state transition model was constructed to simulate
costs and health benefits over lifetime. The primary outcome was costs per
quality-adjusted life-year (QALY) gained. The analysis had the perspective of the
Quebec public healthcare system. RESULTS: A total of 130 patients were randomly
allocated to OL-HDF (n = 67) and LF-HD (n = 63). The cost-utility ratio of OL-HDF
versus LF-HD was Can$53,270 per QALY gained over lifetime. This ratio was fairly
robust in the sensitivity analysis. The cost-utility ratio was lower than that of
LF-HD compared with no treatment (immediate death), which was Can$93,008 per QALY
gained. CONCLUSIONS: High-efficiency OL-HDF can be considered a cost-effective
treatment for ESRD in a Canadian setting. Further research is needed to assess
cost effectiveness in other settings and healthcare systems.