Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1073/pnas.1505962112 http://scihub22266oqcxt.onion/10.1073/pnas.1505962112 C4655533!4655533!26578789     free     free     free Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 261.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 261.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26578789.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Proc+Natl+Acad+Sci+U+S+A 2015 ; 112 (46): E6293-300 Nephropedia Template TP {{tp|p=26578789|t=2015. Telomeric repeat-containing RNA (TERRA) constitutes a nucleoprotein component of extracellular inflammatory exosomes |pdf=|usr=}}{{26578789}} gab.com Text Telomeric repeat-containing RNA (TERRA) constitutes a nucleoprotein component of extracellular inflammatory exosomes JO: Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=26578789 #FOAvip Loss of telomere repeats leads to cellular senescence and the secretion of inflammatory cytokines. How telomere dysfunction is linked to this inflammatory phenotype and its role in aging and cancer is not yet understood. We show here that noncoding telomere RNA transcripts [telomeric repeat-containing RNA (TERRA)] are secreted into the extracellular environment in exosome vesicle fractions. This cell-free TERRA (cfTERRA) is shorter and more stable than intracellular TERRA, is associated with histone proteins, and can induce inflammatory cytokines in responsive cells. These findings suggest that TERRA can have a cell extrinsic function and provide a mechanism through which telomere dysfunction can lead to the activation of inflammatory cytokine signals in the tissue microenvironment through the signaling capacity of cfTERRA. Twit Text FOAVip Telomeric repeat-containing RNA (TERRA) constitutes a nucleoprotein component of extracellular inflammatory exosomes ????Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=26578789 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26578789 #FOAvip English Wikipedia <ref>{{Cite pmid|26578789}}</ref> Telomeric repeat-containing RNA (TERRA) constitutes a nucleoprotein component of extracellular inflammatory exosomes #MMPMID26578789 Wang Z; Deng Z; Dahmane N; Tsai K; Wang P; Williams DR; Kossenkov AV; Showe LC; Zhang R; Huang Q; Conejo-Garcia JR; Lieberman PM Proc Natl Acad Sci U S A 2015[Nov]; 112 (46): E6293-300 PMID26578789show ga Loss of telomere repeats leads to cellular senescence and the secretion of inflammatory cytokines. How telomere dysfunction is linked to this inflammatory phenotype and its role in aging and cancer is not yet understood. We show here that noncoding telomere RNA transcripts [telomeric repeat-containing RNA (TERRA)] are secreted into the extracellular environment in exosome vesicle fractions. This cell-free TERRA (cfTERRA) is shorter and more stable than intracellular TERRA, is associated with histone proteins, and can induce inflammatory cytokines in responsive cells. These findings suggest that TERRA can have a cell extrinsic function and provide a mechanism through which telomere dysfunction can lead to the activation of inflammatory cytokine signals in the tissue microenvironment through the signaling capacity of cfTERRA. äTelomeric repeat-containing RNA (TERRA) constitutes a nucleoprotein co(epmc).pdf DeepDyve Pubget Overpricing