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Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Expert+Rev+Clin+Immunol 2014 ; 10 (10): 1349-56 Nephropedia Template TP
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Biomarkers of sepsis and their potential value in diagnosis, prognosis and treatment #MMPMID25142036
Sandquist M; Wong HR
Expert Rev Clin Immunol 2014[Oct]; 10 (10): 1349-56 PMID25142036show ga
Biomarkers have great potential to improve the diagnosis and treatment of sepsis. The available literature supports the potential utility of sTREM-1, IL-27, suPAR, neutrophil CD64, presepsin, cfDNA and miRNAs as novel diagnostic, prognostic and treatment response biomarkers. The future of sepsis biomarkers lies in extensive validation studies of such novel biomarkers across heterogeneous populations and exploration of their power in combination. Furthermore, the use of a companion diagnostics model may augment the ability of investigators to identify novel sepsis biomarkers and develop specific therapeutic strategies based on biomarker information.