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10.1074/jbc.M115.676072 http://scihub22266oqcxt.onion/10.1074/jbc.M115.676072 C4653689!4653689!26221033     free     free     free Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 263.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Biol+Chem 2015 ; 290 (47): 28343-52 Nephropedia Template TP {{tp|p=26221033|t=2015. Amyloid Oligomers and Mature Fibrils Prepared from an Innocuous Protein Cause Diverging Cellular Death Mechanisms* |pdf=|usr=}}{{26221033}} gab.com Text Amyloid Oligomers and Mature Fibrils Prepared from an Innocuous Protein Cause Diverging Cellular Death Mechanisms* JO: J Biol Chem http://www.kidney.de/pget.php?&tw=1&pmid=26221033 #FOAvip Background: Although oligomers are considered more important, mature fibrils also show evidence as cytotoxic agents in neurodegenerative diseases.Results: Oligomers and fibrils both kill PC12 cells albeit mechanistically differently. In vivo, only oligomers inhibit hippocampal long term potentiation.Conclusion: Protein aggregates, even those irrelevant to disease, are capable of inducing different toxic actions in neuronal cells.Significance: Understanding these toxic mechanisms is vital in improving amyloidosis therapy. Twit Text FOAVip Amyloid Oligomers and Mature Fibrils Prepared from an Innocuous Protein Cause Diverging Cellular Death Mechanisms* ????J Biol Chem http://www.kidney.de/pget.php?&tw=1&pmid=26221033 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26221033 #FOAvip English Wikipedia <ref>{{Cite pmid|26221033}}</ref> Amyloid Oligomers and Mature Fibrils Prepared from an Innocuous Protein Cause Diverging Cellular Death Mechanisms* #MMPMID26221033 Harte NP; Klyubin I; McCarthy EK; Min S; Garrahy SA; Xie Y; Davey GP; Boland JJ; Rowan MJ; Mok KH J Biol Chem 2015[Nov]; 290 (47): 28343-52 PMID26221033show ga Background: Although oligomers are considered more important, mature fibrils also show evidence as cytotoxic agents in neurodegenerative diseases.Results: Oligomers and fibrils both kill PC12 cells albeit mechanistically differently. In vivo, only oligomers inhibit hippocampal long term potentiation.Conclusion: Protein aggregates, even those irrelevant to disease, are capable of inducing different toxic actions in neuronal cells.Significance: Understanding these toxic mechanisms is vital in improving amyloidosis therapy. äAmyloid Oligomers and Mature Fibrils Prepared from an Innocuous Protei(epmc).pdf DeepDyve Pubget Overpricing