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10.1074/jbc.M115.678839 http://scihub22266oqcxt.onion/10.1074/jbc.M115.678839 C4653662!4653662!26359493     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 276.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 276.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 276.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 276.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 276.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Biol+Chem 2015 ; 290 (47): 28020-36 Nephropedia Template TP {{tp|p=26359493|t=2015. Saturation Mutagenesis of the Antithrombin Reactive Center Loop P14 Residue Supports a Three-step Mechanism of Heparin Allosteric Activation Involving Intermediate and Fully Activated States*? |pdf=|usr=}}{{26359493}} gab.com Text Saturation Mutagenesis of the Antithrombin Reactive Center Loop P14 Residue Supports a Three-step Mechanism of Heparin Allosteric Activation Involving Intermediate and Fully Activated States* JO: J Biol Chem http://www.kidney.de/pget.php?&tw=1&pmid=26359493 #FOAvip Background: Structural changes in the antithrombin reactive center loop P14 residue are thought to mediate heparin allosteric activation.Results: P14 residue mutations produced antithrombin activating effects indicative of multiple allosteric activation states.Conclusion: Heparin allosterically activates antithrombin by a minimal three-step mechanism involving intermediate and fully activated states.Significance: New insights into the allosteric activation mechanism of a critical anticoagulant protein are gained. Twit Text FOAVip Saturation Mutagenesis of the Antithrombin Reactive Center Loop P14 Residue Supports a Three-step Mechanism of Heparin Allosteric Activation Involving Intermediate and Fully Activated States* ????J Biol Chem http://www.kidney.de/pget.php?&tw=1&pmid=26359493 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26359493 #FOAvip English Wikipedia <ref>{{Cite pmid|26359493}}</ref> Saturation Mutagenesis of the Antithrombin Reactive Center Loop P14 Residue Supports a Three-step Mechanism of Heparin Allosteric Activation Involving Intermediate and Fully Activated States*? #MMPMID26359493 Roth R; Swanson R; Izaguirre G; Bock SC; Gettins PGW; Olson ST J Biol Chem 2015[Nov]; 290 (47): 28020-36 PMID26359493show ga Background: Structural changes in the antithrombin reactive center loop P14 residue are thought to mediate heparin allosteric activation.Results: P14 residue mutations produced antithrombin activating effects indicative of multiple allosteric activation states.Conclusion: Heparin allosterically activates antithrombin by a minimal three-step mechanism involving intermediate and fully activated states.Significance: New insights into the allosteric activation mechanism of a critical anticoagulant protein are gained. äSaturation Mutagenesis of the Antithrombin Reactive Center Loop P14 Re(epmc).pdf DeepDyve Pubget Overpricing