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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Clin+Infect+Dis
2014 ; 59
(11
): 1588-92
Nephropedia Template TP
gab.com Text
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English Wikipedia
Treating progressive multifocal leukoencephalopathy with interleukin 7 and
vaccination with JC virus capsid protein VP1
#MMPMID25214510
Sospedra M
; Schippling S
; Yousef S
; Jelcic I
; Bofill-Mas S
; Planas R
; Stellmann JP
; Demina V
; Cinque P
; Garcea R
; Croughs T
; Girones R
; Martin R
Clin Infect Dis
2014[Dec]; 59
(11
): 1588-92
PMID25214510
show ga
Progressive multifocal leukoencephalopathy is a currently untreatable infection
of the brain. Here, we demonstrate in 2 patients that treatment with interleukin
7, JC polyomavirus (JCV) capsid protein VP1, and a Toll-like receptor 7 agonist
used as adjuvant, was well tolerated, and showed a very favorable safety profile
and unexpected efficacy that warrant further investigation.