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10.1128/AAC.01885-15 http://scihub22266oqcxt.onion/10.1128/AAC.01885-15 C4649212!4649212 !26369969     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26369969 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Antimicrob+Agents+Chemother 2015 ; 59 (12 ): 7255-64 Nephropedia Template TP {{tp|p=26369969 |t=2015. Assessment of Antiviral Properties of Peramivir against H7N9 Avian Influenza Virus in an Experimental Mouse Model |pdf=|usr=}}{{26369969 }} gab.com Text Assessment of Antiviral Properties of Peramivir against H7N9 Avian Influenza Virus in an Experimental Mouse Model JO: Antimicrob Agents Chemother http://www.kidney.de/pget.php?&tw=1&pmid=26369969 #FOAvip The H7N9 influenza virus causes a severe form of disease in humans. Neuraminidase inhibitors, including oral oseltamivir and injectable peramivir, are the first choices of antiviral treatment for such cases; however, the clinical efficacy of these drugs is questionable. Animal experimental models are essential for understanding the viral replication kinetics under the selective pressure of antiviral agents. This study demonstrates the antiviral activity of peramivir in a mouse model of H7N9 avian influenza virus infection. The data show that repeated administration of peramivir at 30 mg/kg of body weight successfully eradicated the virus from the respiratory tract and extrapulmonary tissues during the acute response, prevented clinical signs of the disease, including neuropathy, and eventually protected mice against lethal H7N9 influenza virus infection. Early treatment with peramivir was found to be associated with better disease outcomes. Twit Text FOAVip Assessment of Antiviral Properties of Peramivir against H7N9 Avian Influenza Virus in an Experimental Mouse Model ????Antimicrob Agents Chemother http://www.kidney.de/pget.php?&tw=1&pmid=26369969 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26369969 #FOAvip English Wikipedia <ref>{{Cite pmid|26369969 }}</ref> Assessment of Antiviral Properties of Peramivir against H7N9 Avian Influenza Virus in an Experimental Mouse Model #MMPMID26369969 Farooqui A ; Huang L ; Wu S ; Cai Y ; Su M ; Lin P ; Chen W ; Fang X ; Zhang L ; Liu Y ; Zeng T ; Paquette SG ; Khan A ; Kelvin AA ; Kelvin DJ Antimicrob Agents Chemother 2015[Dec]; 59 (12 ): 7255-64 PMID26369969 show ga The H7N9 influenza virus causes a severe form of disease in humans. Neuraminidase inhibitors, including oral oseltamivir and injectable peramivir, are the first choices of antiviral treatment for such cases; however, the clinical efficacy of these drugs is questionable. Animal experimental models are essential for understanding the viral replication kinetics under the selective pressure of antiviral agents. This study demonstrates the antiviral activity of peramivir in a mouse model of H7N9 avian influenza virus infection. The data show that repeated administration of peramivir at 30 mg/kg of body weight successfully eradicated the virus from the respiratory tract and extrapulmonary tissues during the acute response, prevented clinical signs of the disease, including neuropathy, and eventually protected mice against lethal H7N9 influenza virus infection. Early treatment with peramivir was found to be associated with better disease outcomes. |Acids, Carbocyclic [MESH] |Animals [MESH] |Antiviral Agents/*pharmacology [MESH] |Cyclopentanes/*pharmacology [MESH] |Dogs [MESH] |Drug Administration Schedule [MESH] |Enzyme Inhibitors/*pharmacology [MESH] |Female [MESH] |Guanidines/*pharmacology [MESH] |Humans [MESH] |Influenza A Virus, H7N9 Subtype/*drug effects/enzymology/growth & development [MESH] |Injections, Intramuscular [MESH] |Lung/drug effects/pathology/virology [MESH] |Madin Darby Canine Kidney Cells [MESH] |Mice [MESH] |Mice, Inbred C57BL [MESH] |Neuraminidase/antagonists & inhibitors/metabolism [MESH] |Orthomyxoviridae Infections/*drug therapy/mortality/pathology/virology [MESH] |Oseltamivir/pharmacology [MESH] |Survival Analysis [MESH] |Treatment Outcome [MESH] |Viral Load/drug effects [MESH] |Viral Proteins/antagonists & inhibitors/metabolism [MESH]Assessment of Antiviral Properties of Peramivir against H7N9 Avian Inf(epmc).pdf DeepDyve Pubget Overpricing