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10.1038/nrendo.2014.166 http://scihub22266oqcxt.onion/10.1038/nrendo.2014.166 C4648246!4648246!25287283     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Nat+Rev+Endocrinol 2015 ; 11 (1): 14-28 Nephropedia Template TP {{tp|p=25287283|t=2015. Regulation of the adrenocortical stem cell niche: implications for disease |pdf=|usr=}}{{25287283}} gab.com Text Regulation of the adrenocortical stem cell niche: implications for disease JO: Nat Rev Endocrinol http://www.kidney.de/pget.php?&tw=1&pmid=25287283 #FOAvip Stem cells are endowed with the potential for self-renewal and multipotency. Pluripotent embryonic stem cells have an early role in the formation of the three germ layers (ectoderm, mesoderm and endoderm), whereas adult tissue stem cells and progenitor cells are critical mediators of organ homeostasis. The adrenal cortex is an exceptionally dynamic endocrine organ that is homeostatically maintained by paracrine and endocrine signals throughout postnatal life. In the past decade, much has been learned about the stem and progenitor cells of the adrenal cortex and the multiple roles that these cell populations have in normal development and homeostasis of the adrenal gland and in adrenal diseases. In this Review, we discuss the evidence for the presence of adrenocortical stem cells, as well as the various signalling molecules and transcriptional networks that are critical for the embryological establishment and postnatal maintenance of this vital population of cells. The implications of these pathways and cells in the pathophysiology of disease are also addressed. Twit Text FOAVip Regulation of the adrenocortical stem cell niche: implications for disease ????Nat Rev Endocrinol http://www.kidney.de/pget.php?&tw=1&pmid=25287283 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25287283 #FOAvip English Wikipedia <ref>{{Cite pmid|25287283}}</ref> Regulation of the adrenocortical stem cell niche: implications for disease #MMPMID25287283 Walczak EM; Hammer GD Nat Rev Endocrinol 2015[Jan]; 11 (1): 14-28 PMID25287283show ga Stem cells are endowed with the potential for self-renewal and multipotency. Pluripotent embryonic stem cells have an early role in the formation of the three germ layers (ectoderm, mesoderm and endoderm), whereas adult tissue stem cells and progenitor cells are critical mediators of organ homeostasis. The adrenal cortex is an exceptionally dynamic endocrine organ that is homeostatically maintained by paracrine and endocrine signals throughout postnatal life. In the past decade, much has been learned about the stem and progenitor cells of the adrenal cortex and the multiple roles that these cell populations have in normal development and homeostasis of the adrenal gland and in adrenal diseases. In this Review, we discuss the evidence for the presence of adrenocortical stem cells, as well as the various signalling molecules and transcriptional networks that are critical for the embryological establishment and postnatal maintenance of this vital population of cells. The implications of these pathways and cells in the pathophysiology of disease are also addressed. äRegulation of the adrenocortical stem cell niche: implications for dis(epmc).pdf DeepDyve Pubget Overpricing