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10.1038/aps.2015.92 http://scihub22266oqcxt.onion/10.1038/aps.2015.92 C4648179!4648179!26388155     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26388155&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Acta+Pharmacol+Sin 2015 ; 36 (10): 1219-27 Nephropedia Template TP {{tp|p=26388155|t=2015. Intra-tumor heterogeneity of cancer cells and its implications for cancer treatment |pdf=|usr=}}{{26388155}} gab.com Text Intra-tumor heterogeneity of cancer cells and its implications for cancer treatment JO: Acta Pharmacol Sin http://www.kidney.de/pget.php?&tw=1&pmid=26388155 #FOAvip Recent studies have revealed extensive genetic and non-genetic variation across different geographical regions of a tumor or throughout different stages of tumor progression, which is referred to as intra-tumor heterogeneity. Several causes contribute to this phenomenon, including genomic instability, epigenetic alteration, plastic gene expression, signal transduction, and microenvironmental differences. These variables may affect key signaling pathways that regulate cancer cell growth, drive phenotypic diversity, and pose challenges to cancer treatment. Understanding the mechanisms underlying this heterogeneity will support the development of effective therapeutic strategies. Twit Text FOAVip Intra-tumor heterogeneity of cancer cells and its implications for cancer treatment ????Acta Pharmacol Sin http://www.kidney.de/pget.php?&tw=1&pmid=26388155 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26388155 #FOAvip English Wikipedia <ref>{{Cite pmid|26388155}}</ref> Intra-tumor heterogeneity of cancer cells and its implications for cancer treatment #MMPMID26388155 Sun Xx; Yu Q Acta Pharmacol Sin 2015[Oct]; 36 (10): 1219-27 PMID26388155show ga Recent studies have revealed extensive genetic and non-genetic variation across different geographical regions of a tumor or throughout different stages of tumor progression, which is referred to as intra-tumor heterogeneity. Several causes contribute to this phenomenon, including genomic instability, epigenetic alteration, plastic gene expression, signal transduction, and microenvironmental differences. These variables may affect key signaling pathways that regulate cancer cell growth, drive phenotypic diversity, and pose challenges to cancer treatment. Understanding the mechanisms underlying this heterogeneity will support the development of effective therapeutic strategies. äIntra-tumor heterogeneity of cancer cells and its implications for can(epmc).pdf DeepDyve Pubget Overpricing