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Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Genomics 2007 ; 89 (3): 307-15 Nephropedia Template TP
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hORFeome v3 1: A resource of human open reading frames representing over 10,000 human genes #MMPMID17207965
Lamesch P; Li N; Milstein S; Fan C; Hao T; Szabo G; Hu Z; Venkatesan K; Bethel G; Martin P; Rogers J; Lawlor S; McLaren S; Dricot A; Borick H; Cusick ME; Vandenhaute J; Dunham I; Hill DE; Vidal M
Genomics 2007[Mar]; 89 (3): 307-15 PMID17207965show ga
Complete sets of cloned protein-encoding open reading frames (ORFs), or ORFeomes, are essential tools for large-scale proteomics and systems biology studies. Here we describe human ORFeome version 3.1 (hORFeome v3.1), currently the largest publicly available resource of full-length human ORFs (available at www.openbiosystems.com). Generated by Gateway recombinational cloning, this collection contains 12,212 ORFs, representing 10,214 human genes, and corresponds to a 51% expansion of the original hORFeome v1.1. An online human ORFeome database, hORFDB, was built and serves as the central repository for all cloned human ORFs (http://horfdb.dfci.harvard.edu). This expansion of the original ORFeome resource greatly increases the potential experimental search space for large-scale proteomics studies, which will lead to the generation of more comprehensive datasets.