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10.1101/gad.268128.115

http://scihub22266oqcxt.onion/10.1101/gad.268128.115
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C4647558!4647558!26545811
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suck abstract from ncbi


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pmid26545811      Genes+Dev 2015 ; 29 (21): 2244-57
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  • WSB1 promotes tumor metastasis by inducing pVHL degradation #MMPMID26545811
  • Kim JJ; Lee SB; Jang J; Yi SY; Kim SH; Han SA; Lee JM; Tong SY; Vincelette ND; Gao B; Yin P; Evans D; Choi DW; Qin B; Liu T; Zhang H; Deng M; Jen J; Zhang J; Wang L; Lou Z
  • Genes Dev 2015[Nov]; 29 (21): 2244-57 PMID26545811show ga
  • In this study, Kim et al. identified WD repeat and SOCS box-containing protein 1 (WSB1) as a novel regulator of pVHL through WSB1's E3 ligase activity. These findings provide important new insights into the understanding of misregulation of the pVHL?HIF pathway in cancer cell invasion and metastasis.
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