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10.3238/arztebl.2015.0730 http://scihub22266oqcxt.onion/10.3238/arztebl.2015.0730 C4647313!4647313!26568177     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26568177&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Dtsch+Arztebl+Int 2015 ; 112 (43): 730-5 Nephropedia Template TP {{tp|p=26568177|t=2015. Screening and Treatment in Retinopathy of Prematurity |pdf=|usr=}}{{26568177}} gab.com Text Screening and Treatment in Retinopathy of Prematurity JO: Dtsch Arztebl Int http://www.kidney.de/pget.php?&tw=1&pmid=26568177 #FOAvip Background: More than 11 000 children are examined for possible retinopathy of prematurity in Germany each year, and 2?5% of them are treated for it. Even though screening and treatment programs are in place, the affected children can still suffer visual impairment. Methods: In this article, we summarize the pathogenesis, screening, and treatment of retinopathy of prematurity on the basis of a selective review of pertinent literature, retrieved by a PubMed search. The article centers on publications from 2011 to 2015 on the new option of treatment with VEGF inhibitors and discusses it in comparison to laser therapy. Results: All premature neonates with a low gestational age at birth, low birth weight, or prolonged exposure to supplemental oxygen must undergo screening by an ophthalmologist. Laser therapy is effective for stages 1?3 and for aggressive posterior retinopathy of prematurity. Its disadvantages are the induction of scarring and the development of severe myopia in 17?40% of the children so treated. Anti-VEGF treatment (VEGF = vascular endothelial growth factor) does not induce any visible scarring and seems to cause less myopia, but long-term data on safety, dosing, and the choice of anti-VEGF drug are still lacking. Conclusion: The available evidence for anti-VEGF treatment is on a much lower level than the evidence for laser therapy. Anti-VEGF may be a way to avoid the disadvantages of laser therapy (scarring and severe myopia). Unlike laser therapy, however, the intravitreal injection of VEGF inhibitors may suppress systemic VEGF levels and potentially harm the developing brain, lungs, or other organs. The currently open questions about anti-VEGF treatment concern its dosing, choice of drug, and long-term safety. Twit Text FOAVip Screening and Treatment in Retinopathy of Prematurity ????Dtsch Arztebl Int http://www.kidney.de/pget.php?&tw=1&pmid=26568177 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26568177 #FOAvip English Wikipedia <ref>{{Cite pmid|26568177}}</ref> Screening and Treatment in Retinopathy of Prematurity #MMPMID26568177 Stahl A; Göpel W Dtsch Arztebl Int 2015[Oct]; 112 (43): 730-5 PMID26568177show ga Background: More than 11 000 children are examined for possible retinopathy of prematurity in Germany each year, and 2?5% of them are treated for it. Even though screening and treatment programs are in place, the affected children can still suffer visual impairment. Methods: In this article, we summarize the pathogenesis, screening, and treatment of retinopathy of prematurity on the basis of a selective review of pertinent literature, retrieved by a PubMed search. The article centers on publications from 2011 to 2015 on the new option of treatment with VEGF inhibitors and discusses it in comparison to laser therapy. Results: All premature neonates with a low gestational age at birth, low birth weight, or prolonged exposure to supplemental oxygen must undergo screening by an ophthalmologist. Laser therapy is effective for stages 1?3 and for aggressive posterior retinopathy of prematurity. Its disadvantages are the induction of scarring and the development of severe myopia in 17?40% of the children so treated. Anti-VEGF treatment (VEGF = vascular endothelial growth factor) does not induce any visible scarring and seems to cause less myopia, but long-term data on safety, dosing, and the choice of anti-VEGF drug are still lacking. Conclusion: The available evidence for anti-VEGF treatment is on a much lower level than the evidence for laser therapy. Anti-VEGF may be a way to avoid the disadvantages of laser therapy (scarring and severe myopia). Unlike laser therapy, however, the intravitreal injection of VEGF inhibitors may suppress systemic VEGF levels and potentially harm the developing brain, lungs, or other organs. The currently open questions about anti-VEGF treatment concern its dosing, choice of drug, and long-term safety. äScreening and Treatment in Retinopathy of Prematurity (epmc).pdf DeepDyve Pubget Overpricing