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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Arch+Pediatr+Adolesc+Med
2010 ; 164
(1
): 61-5
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Survival sex work involvement as a primary risk factor for hepatitis C virus
acquisition in drug-using youths in a canadian setting
#MMPMID20048243
Shannon K
; Kerr T
; Marshall B
; Li K
; Zhang R
; Strathdee SA
; Tyndall MW
; Montaner JG
; Wood E
Arch Pediatr Adolesc Med
2010[Jan]; 164
(1
): 61-5
PMID20048243
show ga
OBJECTIVE: To examine whether there were differential rates of hepatitis C virus
(HCV) incidence in injecting drug-using youths who did and did not report
involvement in survival sex work. DESIGN: Data were derived from 2 prospective
cohort studies of injecting drug users (May 1, 1996, to July 31, 2007). Analyses
were restricted to HCV antibody-negative youths who completed baseline and at
least 1 follow-up assessment. SETTING: Vancouver, British Columbia, Canada.
PARTICIPANTS: Of 3074 injecting drug users, 364 (11.8%) were youths (aged 14-24
years) with a median age of 21.3 years and a duration of injecting drug use of 3
years. Main Exposure Survival sex work involvement. MAIN OUTCOME MEASURE: The
Kaplan-Meier method and Cox proportional hazards regression were used to compare
HCV incidence among youths who did and did not report survival sex work. RESULTS:
Baseline HCV prevalence was 51%, with youths involved in survival sex work
significantly more likely to be HCV antibody positive (60% vs 44%; P = .002). In
baseline HCV antibody-negative youths, the cumulative HCV incidence at 36 months
was significantly higher in those involved in survival sex work (68.4% vs 38.8%;
P < .001). The HCV incidence density was 36.8 (95% confidence interval [CI],
24.2-53.5) per 100 person-years in youths reporting survival sex work involvement
at baseline compared with 14.1 (9.4-20.3) per 100 person-years in youths not
reporting survival sex work. In multivariate Cox proportional hazards analyses,
survival sex work was the strongest predictor of elevated HCV incidence (adjusted
relative hazard, 2.30; 95% CI, 1.27-4.15). CONCLUSION: This study calls attention
to the critical need for evidence-based social and structural HCV prevention
efforts that target youths engaged in survival sex work.
|Adolescent
[MESH]
|Adult
[MESH]
|British Columbia/epidemiology
[MESH]
|Female
[MESH]
|Hepatitis C/*epidemiology/transmission
[MESH]
|Homeless Youth/*statistics & numerical data
[MESH]