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10.1001/archpediatrics.2009.241

http://scihub22266oqcxt.onion/10.1001/archpediatrics.2009.241
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suck abstract from ncbi


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pmid20048243
      Arch+Pediatr+Adolesc+Med 2010 ; 164 (1 ): 61-5
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  • Survival sex work involvement as a primary risk factor for hepatitis C virus acquisition in drug-using youths in a canadian setting #MMPMID20048243
  • Shannon K ; Kerr T ; Marshall B ; Li K ; Zhang R ; Strathdee SA ; Tyndall MW ; Montaner JG ; Wood E
  • Arch Pediatr Adolesc Med 2010[Jan]; 164 (1 ): 61-5 PMID20048243 show ga
  • OBJECTIVE: To examine whether there were differential rates of hepatitis C virus (HCV) incidence in injecting drug-using youths who did and did not report involvement in survival sex work. DESIGN: Data were derived from 2 prospective cohort studies of injecting drug users (May 1, 1996, to July 31, 2007). Analyses were restricted to HCV antibody-negative youths who completed baseline and at least 1 follow-up assessment. SETTING: Vancouver, British Columbia, Canada. PARTICIPANTS: Of 3074 injecting drug users, 364 (11.8%) were youths (aged 14-24 years) with a median age of 21.3 years and a duration of injecting drug use of 3 years. Main Exposure Survival sex work involvement. MAIN OUTCOME MEASURE: The Kaplan-Meier method and Cox proportional hazards regression were used to compare HCV incidence among youths who did and did not report survival sex work. RESULTS: Baseline HCV prevalence was 51%, with youths involved in survival sex work significantly more likely to be HCV antibody positive (60% vs 44%; P = .002). In baseline HCV antibody-negative youths, the cumulative HCV incidence at 36 months was significantly higher in those involved in survival sex work (68.4% vs 38.8%; P < .001). The HCV incidence density was 36.8 (95% confidence interval [CI], 24.2-53.5) per 100 person-years in youths reporting survival sex work involvement at baseline compared with 14.1 (9.4-20.3) per 100 person-years in youths not reporting survival sex work. In multivariate Cox proportional hazards analyses, survival sex work was the strongest predictor of elevated HCV incidence (adjusted relative hazard, 2.30; 95% CI, 1.27-4.15). CONCLUSION: This study calls attention to the critical need for evidence-based social and structural HCV prevention efforts that target youths engaged in survival sex work.
  • |Adolescent [MESH]
  • |Adult [MESH]
  • |British Columbia/epidemiology [MESH]
  • |Female [MESH]
  • |Hepatitis C/*epidemiology/transmission [MESH]
  • |Homeless Youth/*statistics & numerical data [MESH]
  • |Humans [MESH]
  • |Incidence [MESH]
  • |Male [MESH]
  • |Prevalence [MESH]
  • |Proportional Hazards Models [MESH]
  • |Risk Factors [MESH]
  • |Sex Work/*statistics & numerical data [MESH]


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