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10.1074/jbc.M115.649582

http://scihub22266oqcxt.onion/10.1074/jbc.M115.649582
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C4646406!4646406!26400081
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suck abstract from ncbi


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pmid26400081      J+Biol+Chem 2015 ; 290 (45): 27101-12
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  • Antigen-B Cell Receptor Complexes Associate with Intracellular major histocompatibility complex (MHC) Class II Molecules* #MMPMID26400081
  • Barroso M; Tucker H; Drake L; Nichol K; Drake JR
  • J Biol Chem 2015[Nov]; 290 (45): 27101-12 PMID26400081show ga
  • Background: Mechanisms that preferentially deliver B cell receptor-antigen complexes to receptive MHC class II molecules are poorly defined.Results: Internalized B cell receptor-antigen complexes associate with class II molecules.Conclusion: In B cells, B cell receptor-antigen complexes associate with peptide-loaded class II molecules, potentially defining sites of class II ligand acquisition.Significance: Antigen-specific B cells control the loading of cognate antigen-derived peptide onto class II molecules.
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