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10.1074/jbc.M115.642900

http://scihub22266oqcxt.onion/10.1074/jbc.M115.642900
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C4646026!4646026!26429917
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suck abstract from ncbi


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pmid26429917      J+Biol+Chem 2015 ; 290 (46): 27803-15
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  • Syk Is Recruited to Stress Granules and Promotes Their Clearance through Autophagy* #MMPMID26429917
  • Krisenko MO; Higgins RL; Ghosh S; Zhou Q; Trybula JS; Wang WH; Geahlen RL
  • J Biol Chem 2015[Nov]; 290 (46): 27803-15 PMID26429917show ga
  • Background: Syk associates with proteins that are found in stress granules.Results: Stress granules contain Syk, Grb7, and phosphotyrosine and persist in cells treated with inhibitors of autophagy.Conclusion: Syk is recruited to stress granules and promotes their clearance through autophagy.Significance: The regulation of both stress granule clearance and autophagy is important for the survival of cells exposed to external stress.
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