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10.1074/jbc.M115.660761

http://scihub22266oqcxt.onion/10.1074/jbc.M115.660761
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C4646013!4646013!26363073
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suck abstract from ncbi


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pmid26363073      J+Biol+Chem 2015 ; 290 (46): 27618-32
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  • Encephalomyocarditis Virus 3C Protease Relieves TRAF Family Member-associated NF-?B Activator (TANK) Inhibitory Effect on TRAF6-mediated NF-?B Signaling through Cleavage of TANK* #MMPMID26363073
  • Huang L; Liu Q; Zhang L; Zhang Q; Hu L; Li C; Wang S; Li J; Zhang Y; Yu H; Wang Y; Zhong Z; Xiong T; Xia X; Wang X; Yu L; Deng G; Cai X; Cui S; Weng C
  • J Biol Chem 2015[Nov]; 290 (46): 27618-32 PMID26363073show ga
  • Background: TANK is a negative regulator of canonical NF-?B signaling.Results: EMCV 3C cleaves TANK and regulates NF-?B activation.Conclusion: EMCV 3C relieves TANK inhibitory effect on TRAF6-mediated NF-?B signaling pathway.Significance: TANK is a novel target protein of viral proteases encoded by several positive RNA viruses.
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