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10.1186/s13054-015-1100-9

http://scihub22266oqcxt.onion/10.1186/s13054-015-1100-9
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suck abstract from ncbi


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pmid26563768
      Crit+Care 2015 ; 19 (ä): 400
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  • Does inferior vena cava respiratory variability predict fluid responsiveness in spontaneously breathing patients? #MMPMID26563768
  • Airapetian N ; Maizel J ; Alyamani O ; Mahjoub Y ; Lorne E ; Levrard M ; Ammenouche N ; Seydi A ; Tinturier F ; Lobjoie E ; Dupont H ; Slama M
  • Crit Care 2015[Nov]; 19 (ä): 400 PMID26563768 show ga
  • INTRODUCTION: We have almost no information concerning the value of inferior vena cava (IVC) respiratory variations in spontaneously breathing ICU patients (SBP) to predict fluid responsiveness. METHODS: SBP with clinical fluid need were included prospectively in the study. Echocardiography and Doppler ultrasound were used to record the aortic velocity-time integral (VTI), stroke volume (SV), cardiac output (CO) and IVC collapsibility index (cIVC) ((maximum diameter (IVCmax)- minimum diameter (IVCmin))/ IVCmax) at baseline, after a passive leg-raising maneuver (PLR) and after 500 ml of saline infusion. RESULTS: Fifty-nine patients (30 males and 29 females; 57?±?18 years-old) were included in the study. Of these, 29 (49 %) were considered to be responders (?10 % increase in CO after fluid infusion). There were no significant differences between responders and nonresponders at baseline, except for a higher aortic VTI in nonresponders (16 cm vs. 19 cm, p?=?0.03). Responders had a lower baseline IVCmin than nonresponders (11?±?5 mm vs. 14?±?5 mm, p?=?0.04) and more marked IVC variations (cIVC: 35?±?16 vs. 27?±?10 %, p?=?0.04). Prediction of fluid-responsiveness using cIVC and IVCmax was low (area under the curve for cIVC at baseline 0.62?±?0.07; 95 %, CI 0.49-0.74 and for IVCmax at baseline 0.62?±?0.07; 95 % CI 0.49-0.75). In contrast, IVC respiratory variations >42 % in SBP demonstrated a high specificity (97 %) and a positive predictive value (90 %) to predict an increase in CO after fluid infusion. CONCLUSIONS: In SBP with suspected hypovolemia, vena cava size and respiratory variability do not predict fluid responsiveness. In contrast, a cIVC >42 % may predict an increase in CO after fluid infusion.
  • |*Hydrodynamics [MESH]
  • |*Respiratory Physiological Phenomena [MESH]
  • |Adult [MESH]
  • |Aged [MESH]
  • |Cardiac Output/*physiology [MESH]
  • |Female [MESH]
  • |Fluid Therapy/*methods [MESH]
  • |Humans [MESH]
  • |Hypovolemia/*blood/diagnostic imaging [MESH]
  • |Male [MESH]
  • |Middle Aged [MESH]
  • |Prospective Studies [MESH]
  • |Respiration [MESH]
  • |Ultrasonography [MESH]


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