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10.7150/ijms.11579 http://scihub22266oqcxt.onion/10.7150/ijms.11579 C4643073!4643073!26640402     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Int+J+Med+Sci 2015 ; 12 (11): 840-7 Nephropedia Template TP {{tp|p=26640402|t=2015. Role and New Insights of Pirfenidone in Fibrotic Diseases |pdf=|usr=}}{{26640402}} gab.com Text Role and New Insights of Pirfenidone in Fibrotic Diseases JO: Int J Med Sci http://www.kidney.de/pget.php?&tw=1&pmid=26640402 #FOAvip Pirfenidone (PFD) is a non-peptide synthetic molecule issued as a broad-spectrum anti-fibrotic drug with the ability to decrease TGF-?1, TNF-?, PDGF and COL1A1 expression, which is highly related to prevent or remove excessive deposition of scar tissue in several organs. Basic and clinical evidence suggests that PFD may safely slow or inhibit the progressive fibrosis swelling after tissue injuries. Furthermore, a number of evidence suggests that this molecule will have positive effects in the treatment of other inflammatory diseases. This review contains current research in which PFD has been used as the treatment of several diseases, and focus mainly in the outcomes related to improve inflammation and fibrogenesis. Therefore, the main goal of this review is to focus on the novel findings of PFD efficacy rather than deepen in the chemical aspects of the molecule. Twit Text FOAVip Role and New Insights of Pirfenidone in Fibrotic Diseases ????Int J Med Sci http://www.kidney.de/pget.php?&tw=1&pmid=26640402 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26640402 #FOAvip English Wikipedia <ref>{{Cite pmid|26640402}}</ref> Role and New Insights of Pirfenidone in Fibrotic Diseases #MMPMID26640402 Lopez-de la Mora DA; Sanchez-Roque C; Montoya-Buelna M; Sanchez-Enriquez S; Lucano-Landeros S; Macias-Barragan J; Armendariz-Borunda J Int J Med Sci 2015[]; 12 (11): 840-7 PMID26640402show ga Pirfenidone (PFD) is a non-peptide synthetic molecule issued as a broad-spectrum anti-fibrotic drug with the ability to decrease TGF-?1, TNF-?, PDGF and COL1A1 expression, which is highly related to prevent or remove excessive deposition of scar tissue in several organs. Basic and clinical evidence suggests that PFD may safely slow or inhibit the progressive fibrosis swelling after tissue injuries. Furthermore, a number of evidence suggests that this molecule will have positive effects in the treatment of other inflammatory diseases. This review contains current research in which PFD has been used as the treatment of several diseases, and focus mainly in the outcomes related to improve inflammation and fibrogenesis. Therefore, the main goal of this review is to focus on the novel findings of PFD efficacy rather than deepen in the chemical aspects of the molecule. äRole and New Insights of Pirfenidone in Fibrotic Diseases (epmc).pdf DeepDyve Pubget Overpricing