Multisystemic Side Effects of an Indispensable Old Drug: A Case Report of Chronic
Lithium Use (A Patient with Multiple Side Effects of Lithium)
#MMPMID26604931
Demirtas L
; Akbas EM
; Degirmenci H
; Gurel A
; Duzgun E
Case Rep Med
2015[]; 2015
(?): 473931
PMID26604931
show ga
Presented here is a case of long-term lithium use, with multiple emerging
lithium-associated side effects. An 82-year-old woman was brought into the
emergency department because of loss of consciousness. According to the physical
examination and laboratory analyses, patient was diagnosed with
lithium-associated hypercalcemia, hyperparathyroidism, nephrogenic diabetes
insipidus (NDI), symptomatic sinus bradycardia, and thyroid dysfunction. In the
literature, there is a limited number of case reports with lithium induced
multiple clinical conditions. Multiple clinical manifestations due to the side
effects of chronic lithium use might be seen. Health care professionals should
keep in mind that lithium-related side effects might trigger or exacerbate each
other. To avoid toxicity, close follow-up and clinical supervision are important
for the early diagnosis and treatment of these side effects, due to the narrow
therapeutic index and obscure clinical signs and symptoms of toxicity.