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10.1038/jid.2015.252

http://scihub22266oqcxt.onion/10.1038/jid.2015.252
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suck abstract from ncbi


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pmid26134944
      J+Invest+Dermatol 2015 ; 135 (11 ): 2873-2876
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  • Dual mTOR Inhibition Is Required to Prevent TGF-?-Mediated Fibrosis: Implications for Scleroderma #MMPMID26134944
  • Mitra A ; Luna JI ; Marusina AI ; Merleev A ; Kundu-Raychaudhuri S ; Fiorentino D ; Raychaudhuri SP ; Maverakis E
  • J Invest Dermatol 2015[Nov]; 135 (11 ): 2873-2876 PMID26134944 show ga
  • ä
  • |Biomarkers/metabolism [MESH]
  • |Biopsy, Needle [MESH]
  • |Cells, Cultured [MESH]
  • |Fibroblasts [MESH]
  • |Fibrosis/drug therapy/prevention & control [MESH]
  • |Humans [MESH]
  • |Imidazoles/pharmacology [MESH]
  • |Immunohistochemistry [MESH]
  • |Molecular Targeted Therapy [MESH]
  • |Phosphorylation/drug effects [MESH]
  • |Polymerase Chain Reaction/methods [MESH]
  • |Scleroderma, Diffuse/*drug therapy/metabolism/*pathology [MESH]
  • |Sensitivity and Specificity [MESH]
  • |Sirolimus/*pharmacology [MESH]
  • |Smad2 Protein/drug effects/metabolism [MESH]
  • |TOR Serine-Threonine Kinases/drug effects/*metabolism [MESH]
  • |Transforming Growth Factor beta/drug effects/*metabolism [MESH]


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