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10.4049/jimmunol.1402584 http://scihub22266oqcxt.onion/10.4049/jimmunol.1402584 C4640183!4640183!26378073     free     free     free Deprecated: Implicit conversion from float 225.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 225.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 225.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 225.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Immunol 2015 ; 195 (9): 4257-63 Nephropedia Template TP {{tp|p=26378073|t=2015. A stromal cell niche for human and mouse type 3 innate lymphoid cells ¶ |pdf=|usr=}}{{26378073}} gab.com Text A stromal cell niche for human and mouse type 3 innate lymphoid cells ¶ JO: J Immunol http://www.kidney.de/pget.php?&tw=1&pmid=26378073 #FOAvip Adaptive immunity critically depends on the functional compartmentalization of secondary lymphoid organs. Mesenchymal stromal cells create and maintain specialized niches that support survival, activation and expansion of T and B cells, and integrated analysis of lymphocytes and their niche has been instrumental in understanding adaptive immunity. Lymphoid organs are also home to type 3 innate lymphoid cells (ILC3), innate effector cells essential for barrier immunity. However, a specialized stromal niche for ILC3 has not been identified. A novel lineage-tracing approach now identifies a subset of murine fetal lymphoid tissue organizer cells that gives rise exclusively to adult marginal reticular cells (MRC). Moreover, both cell types are conserved from mouse to human and co-localize with ILC3 in secondary lymphoid tissues throughout life. In sum, we provide evidence that fetal stromal organizers give rise to adult MRC and form a dedicated stromal niche for innate ILC3 in adaptive lymphoid organs. Twit Text FOAVip A stromal cell niche for human and mouse type 3 innate lymphoid cells ¶ ????J Immunol http://www.kidney.de/pget.php?&tw=1&pmid=26378073 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26378073 #FOAvip English Wikipedia <ref>{{Cite pmid|26378073}}</ref> A stromal cell niche for human and mouse type 3 innate lymphoid cells ¶ #MMPMID26378073 Hoorweg K; Narang P; Li Z; Thuery A; Papazian N; Withers DR; Coles MC; Cupedo T J Immunol 2015[Nov]; 195 (9): 4257-63 PMID26378073show ga Adaptive immunity critically depends on the functional compartmentalization of secondary lymphoid organs. Mesenchymal stromal cells create and maintain specialized niches that support survival, activation and expansion of T and B cells, and integrated analysis of lymphocytes and their niche has been instrumental in understanding adaptive immunity. Lymphoid organs are also home to type 3 innate lymphoid cells (ILC3), innate effector cells essential for barrier immunity. However, a specialized stromal niche for ILC3 has not been identified. A novel lineage-tracing approach now identifies a subset of murine fetal lymphoid tissue organizer cells that gives rise exclusively to adult marginal reticular cells (MRC). Moreover, both cell types are conserved from mouse to human and co-localize with ILC3 in secondary lymphoid tissues throughout life. In sum, we provide evidence that fetal stromal organizers give rise to adult MRC and form a dedicated stromal niche for innate ILC3 in adaptive lymphoid organs. äA stromal cell niche for human and mouse type 3 innate lymphoid cells (epmc).pdf DeepDyve Pubget Overpricing