Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1186/s12885-015-1906-5 http://scihub22266oqcxt.onion/10.1186/s12885-015-1906-5 C4640103!4640103!26552809     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       BMC+Cancer 2015 ; 15 (ä): ä Nephropedia Template TP {{tp|p=26552809|t=2015. Prognostic significance of ST3GAL-1 expression in patients with clear cell renal cell carcinoma |pdf=|usr=}}{{26552809}} gab.com Text Prognostic significance of ST3GAL-1 expression in patients with clear cell renal cell carcinoma JO: BMC Cancer http://www.kidney.de/pget.php?&tw=1&pmid=26552809 #FOAvip Background: Aberrant sialylated carbohydrate synthesis is frequently noted in various cancers. Sialyltransferase ST3GAL-1, which adds a sialic acid in an ?-2,3 linkage to Gal ?1,3 GalNAc, preforms an important role in modulating cellular behaviors. However, little is known about prognostic significance of ST3GAL-1 in clear cell renal cell carcinoma (ccRCC). In this study, we aimed to investigate the prognostic significance of sialyltransferase ST3GAL-1 and its correlation with clinical outcomes in patients with ccRCC. Methods: A total of 286 patients who underwent nephrectomy between 2005 and 2007 in a single academic center were recruited. Immunohistochemical staining was performed on tissue microarrays to assess the expression level. Kaplan-Meier method and Cox proportional hazard model were applied to assess the prognostic value of ST3GAL-1. Nomograms were generated as prediction model for overall survival and disease free survival at 5 and 8 years after nephrectomy. Results: The present results show high expression of ST3GAL-1 is associated with reduced overall survival (p?=?0.013) and disease free survival (p?=?0.004). In multivariate cox analyses, ST3GAL-1 was defined as an independent prognostic factor for overall survival (p?=?0.006) and disease free survival (p?=?0.001). After incorporation into the University of California Integrated Staging System (UISS) intermediate/high risk group for non-metastatic ccRCC, ST3GAL-1 could further distinguish patient with dismal prognosis (p?=?0.015 and 0.002 for OS and DFS respectively). The nomograms revealed better predictive accuracy in predicting 5- and 8- year overall survival and disease free survival than the TNM stage alone. Conclusions: ST3GAL-1 is an independent adverse prognostic factor for recurrence and survival of patients with ccRCC. Twit Text FOAVip Prognostic significance of ST3GAL-1 expression in patients with clear cell renal cell carcinoma ????BMC Cancer http://www.kidney.de/pget.php?&tw=1&pmid=26552809 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26552809 #FOAvip English Wikipedia <ref>{{Cite pmid|26552809}}</ref> Prognostic significance of ST3GAL-1 expression in patients with clear cell renal cell carcinoma #MMPMID26552809 Bai Q; Liu L; Xia Y; Long Q; Wang J; Xu J; Guo J BMC Cancer 2015[]; 15 (ä): ä PMID26552809show ga Background: Aberrant sialylated carbohydrate synthesis is frequently noted in various cancers. Sialyltransferase ST3GAL-1, which adds a sialic acid in an ?-2,3 linkage to Gal ?1,3 GalNAc, preforms an important role in modulating cellular behaviors. However, little is known about prognostic significance of ST3GAL-1 in clear cell renal cell carcinoma (ccRCC). In this study, we aimed to investigate the prognostic significance of sialyltransferase ST3GAL-1 and its correlation with clinical outcomes in patients with ccRCC. Methods: A total of 286 patients who underwent nephrectomy between 2005 and 2007 in a single academic center were recruited. Immunohistochemical staining was performed on tissue microarrays to assess the expression level. Kaplan-Meier method and Cox proportional hazard model were applied to assess the prognostic value of ST3GAL-1. Nomograms were generated as prediction model for overall survival and disease free survival at 5 and 8 years after nephrectomy. Results: The present results show high expression of ST3GAL-1 is associated with reduced overall survival (p?=?0.013) and disease free survival (p?=?0.004). In multivariate cox analyses, ST3GAL-1 was defined as an independent prognostic factor for overall survival (p?=?0.006) and disease free survival (p?=?0.001). After incorporation into the University of California Integrated Staging System (UISS) intermediate/high risk group for non-metastatic ccRCC, ST3GAL-1 could further distinguish patient with dismal prognosis (p?=?0.015 and 0.002 for OS and DFS respectively). The nomograms revealed better predictive accuracy in predicting 5- and 8- year overall survival and disease free survival than the TNM stage alone. Conclusions: ST3GAL-1 is an independent adverse prognostic factor for recurrence and survival of patients with ccRCC. äPrognostic significance of ST3GAL-1 expression in patients with clear (epmc).pdf DeepDyve Pubget Overpricing