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2015 ; 2
(ä): 59
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gab.com Text
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English Wikipedia
Neonatal Mitral Valve Repair in Biventricular Repair, Single Ventricle
Palliation, and Secondary Left Ventricular Recruitment: Indications, Techniques,
and Mid-Term Outcomes
#MMPMID26618162
Myers PO
; Baird CW
; Del Nido PJ
; Pigula FA
; Lang N
; Marx GR
; Emani SM
Front Surg
2015[]; 2
(ä): 59
PMID26618162
show ga
OBJECTIVES: Although mitral valve repair is rarely required in neonates, this
population is considered to be at high risk for adverse outcomes. The aim of this
study was to review the indications for surgery, mechanisms, repair techniques,
and mid-term outcomes of neonatal mitral valve repair. METHODS: The demographic,
procedural, and outcome data were obtained for all neonates who underwent mitral
valve repair from 2005 to 2012. The primary endpoints included mortality,
transplantation, and mitral valve reoperation. RESULTS: Twenty patients were
included during the study period. Median age at operation was 11?days (range:
3-25). Eleven patients (55%) presented with mitral stenosis, three had
regurgitation (15%), and six had mixed mitral disease (30%). Nineteen of 20
patients had mild or less regurgitation on immediate postoperative imaging.
During a median follow-up of 5?months (1?month-4.8?years), six patients died at a
median of 33?months (7-41?months) from repair and one patient required orthotopic
heart transplantation. Six patients required mitral valve reoperation, five for
mitral valve re-repair, and one for mitral valve replacement. Freedom from death,
transplantation, or mitral valve replacement was 84.2?±?8.4% at 1?month,
71.3?±?11% at 6?months, 64.1?±?12% at 1?year, and 51.3?±?15% at 2?years and was
worse for patients presenting with mitral regurgitation compared to stenosis or
mixed mitral valve disease. CONCLUSION: Although mitral valve repair can be
performed with acceptable immediate postoperative result, this procedure carries
a high burden of late death and mitral valve reoperations.