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http://scihub22266oqcxt.onion/ C4637618!4637618 !26617803     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26617803 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Int+J+Clin+Exp+Pathol 2015 ; 8 (9 ): 10887-93 Nephropedia Template TP {{tp|p=26617803 |t=2015. Pituitary tumor transforming gene PTTG2 induces psoriasis by regulating vimentin and E-cadherin expression |pdf=|usr=}}{{26617803 }} gab.com Text Pituitary tumor transforming gene PTTG2 induces psoriasis by regulating vimentin and E-cadherin expression JO: Int J Clin Exp Pathol http://www.kidney.de/pget.php?&tw=1&pmid=26617803 #FOAvip Psoriasis is a common and intractable skin disease affecting the physical and mental health of patients. This study focused on the roles of pituitary tumor transforming gene 2 (PTTG2) in psoriasis. Using real-time quantitative PCR and western blot, the expression patterns of PTTG2 were compared in psoriatic epidermis cells and normal cells, from both mRNA levels and protein levels. Knockdown of PTTG2 by siRNA was conducted in HaCaT cells to investigate the changes in cell viability and migration in vitro. Expression changes of vimentin and E-cadherin were also detected in the transfected cells. Results showed PTTG2 was significantly overexpressed in the psoriatic epidermis cells (P < 0.05). The cell viability and migration were inhibited by the knockdown of PTTG2. Besides, knockdown of PTTG2 resulted in down-regulation of vimentin and up-regulation of E-cadherin, with significant differences compared to the siRNA control group (P < 0.05). This study indicated the involvement of PTTG2 in mediating epidermis cell viability and migration and in pathogenesis of psoriasis. PTTG2 might be a potential therapeutic target for psoriasis through inducing epithelial-to-mesenchymal transition (EMT) via regulating the expression of vimentin and E-cadherin. Twit Text FOAVip Pituitary tumor transforming gene PTTG2 induces psoriasis by regulating vimentin and E-cadherin expression ????Int J Clin Exp Pathol http://www.kidney.de/pget.php?&tw=1&pmid=26617803 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26617803 #FOAvip English Wikipedia <ref>{{Cite pmid|26617803 }}</ref> Pituitary tumor transforming gene PTTG2 induces psoriasis by regulating vimentin and E-cadherin expression #MMPMID26617803 Liu XB ; Li F ; Li YQ ; Yang F Int J Clin Exp Pathol 2015[]; 8 (9 ): 10887-93 PMID26617803 show ga Psoriasis is a common and intractable skin disease affecting the physical and mental health of patients. This study focused on the roles of pituitary tumor transforming gene 2 (PTTG2) in psoriasis. Using real-time quantitative PCR and western blot, the expression patterns of PTTG2 were compared in psoriatic epidermis cells and normal cells, from both mRNA levels and protein levels. Knockdown of PTTG2 by siRNA was conducted in HaCaT cells to investigate the changes in cell viability and migration in vitro. Expression changes of vimentin and E-cadherin were also detected in the transfected cells. Results showed PTTG2 was significantly overexpressed in the psoriatic epidermis cells (P < 0.05). The cell viability and migration were inhibited by the knockdown of PTTG2. Besides, knockdown of PTTG2 resulted in down-regulation of vimentin and up-regulation of E-cadherin, with significant differences compared to the siRNA control group (P < 0.05). This study indicated the involvement of PTTG2 in mediating epidermis cell viability and migration and in pathogenesis of psoriasis. PTTG2 might be a potential therapeutic target for psoriasis through inducing epithelial-to-mesenchymal transition (EMT) via regulating the expression of vimentin and E-cadherin. |Antigens, CD [MESH] |Cadherins/*metabolism [MESH] |Case-Control Studies [MESH] |Cell Line [MESH] |Cell Movement [MESH] |Cell Survival [MESH] |Epidermis/*metabolism/pathology [MESH] |Epithelial-Mesenchymal Transition [MESH] |Humans [MESH] |Keratinocytes/*metabolism/pathology [MESH] |Psoriasis/genetics/*metabolism/pathology [MESH] |RNA Interference [MESH] |Securin/genetics/*metabolism [MESH] |Time Factors [MESH] |Transfection [MESH]Pituitary tumor transforming gene PTTG2 induces psoriasis by regulatin(epmc).pdf DeepDyve Pubget Overpricing