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10.1111/bpa.12307 http://scihub22266oqcxt.onion/10.1111/bpa.12307 C4636016!4636016!26526943     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Brain+Pathol 2015 ; 25 (6): 755-9 Nephropedia Template TP {{tp|p=26526943|t=2015. mTORC2 and Metabolic Reprogramming in GBM: at the Interface of Genetics and Environment |pdf=|usr=}}{{26526943}} gab.com Text mTORC2 and Metabolic Reprogramming in GBM: at the Interface of Genetics and Environment JO: Brain Pathol http://www.kidney.de/pget.php?&tw=1&pmid=26526943 #FOAvip Metabolic reprogramming is a central hallmark of cancer, enabling tumor cells to obtain the macromolecular precursors and energy needed for rapid tumor growth. Understanding how oncogenes coordinate altered signaling with metabolic reprogramming and how cancer cells harness cellular metabolism and its metabolites for their survival may yield new insights into tumor pathogenesis. Here, we review the recently identified central regulatory role for mTORC2, a downstream effector of many cancer?causing mutations, in metabolic reprogramming and cancer drug resistance in glioblastoma. We further consider the emerging concept that mTORC2 may connect genetics with environmental alterations in brain cancer. Twit Text FOAVip mTORC2 and Metabolic Reprogramming in GBM: at the Interface of Genetics and Environment ????Brain Pathol http://www.kidney.de/pget.php?&tw=1&pmid=26526943 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26526943 #FOAvip English Wikipedia <ref>{{Cite pmid|26526943}}</ref> mTORC2 and Metabolic Reprogramming in GBM: at the Interface of Genetics and Environment #MMPMID26526943 Masui K; Cavenee WK; Mischel PS Brain Pathol 2015[Nov]; 25 (6): 755-9 PMID26526943show ga Metabolic reprogramming is a central hallmark of cancer, enabling tumor cells to obtain the macromolecular precursors and energy needed for rapid tumor growth. Understanding how oncogenes coordinate altered signaling with metabolic reprogramming and how cancer cells harness cellular metabolism and its metabolites for their survival may yield new insights into tumor pathogenesis. Here, we review the recently identified central regulatory role for mTORC2, a downstream effector of many cancer?causing mutations, in metabolic reprogramming and cancer drug resistance in glioblastoma. We further consider the emerging concept that mTORC2 may connect genetics with environmental alterations in brain cancer. ämTORC2 and Metabolic Reprogramming in GBM: at the Interface of Genetic(epmc).pdf DeepDyve Pubget Overpricing