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10.3389/fphar.2015.00262 http://scihub22266oqcxt.onion/10.3389/fphar.2015.00262 C4633676!4633676!26594174     free     free     free       Front+Pharmacol 2015 ; 6 (ä): ä Nephropedia Template TP {{tp|p=26594174|t=2015. NLRP3 inflammasome and its inhibitors: a review |pdf=|usr=}}{{26594174}} gab.com Text NLRP3 inflammasome and its inhibitors: a review JO: Front Pharmacol http://www.kidney.de/pget.php?&tw=1&pmid=26594174 #FOAvip Inflammasomes are newly recognized, vital players in innate immunity. The best characterized is the NLRP3 inflammasome, so-called because the NLRP3 protein in the complex belongs to the family of nucleotide-binding and oligomerization domain-like receptors (NLRs) and is also known as ?pyrin domain-containing protein 3?. The NLRP3 inflammasome is associated with onset and progression of various diseases, including metabolic disorders, multiple sclerosis, inflammatory bowel disease, cryopyrin-associated periodic fever syndrome, as well as other auto-immune and auto-inflammatory diseases. Several NLRP3 inflammasome inhibitors have been described, some of which show promise in the clinic. The present review will describe the structure and mechanisms of activation of the NLRP3 inflammasome, its association with various auto-immune and auto-inflammatory diseases, and the state of research into NLRP3 inflammasome inhibitors. Twit Text FOAVip NLRP3 inflammasome and its inhibitors: a review ????Front Pharmacol http://www.kidney.de/pget.php?&tw=1&pmid=26594174 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26594174 #FOAvip English Wikipedia <ref>{{Cite pmid|26594174}}</ref> NLRP3 inflammasome and its inhibitors: a review #MMPMID26594174 Shao BZ; Xu ZQ; Han BZ; Su DF; Liu C Front Pharmacol 2015[]; 6 (ä): ä PMID26594174show ga Inflammasomes are newly recognized, vital players in innate immunity. The best characterized is the NLRP3 inflammasome, so-called because the NLRP3 protein in the complex belongs to the family of nucleotide-binding and oligomerization domain-like receptors (NLRs) and is also known as ?pyrin domain-containing protein 3?. The NLRP3 inflammasome is associated with onset and progression of various diseases, including metabolic disorders, multiple sclerosis, inflammatory bowel disease, cryopyrin-associated periodic fever syndrome, as well as other auto-immune and auto-inflammatory diseases. Several NLRP3 inflammasome inhibitors have been described, some of which show promise in the clinic. The present review will describe the structure and mechanisms of activation of the NLRP3 inflammasome, its association with various auto-immune and auto-inflammatory diseases, and the state of research into NLRP3 inflammasome inhibitors. äNLRP3 inflammasome and its inhibitors: a review (epmc).pdf DeepDyve Pubget Overpricing