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10.3390/ijms161023651 http://scihub22266oqcxt.onion/10.3390/ijms161023651 C4632719!4632719!26445043     free     free     free Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Int+J+Mol+Sci 2015 ; 16 (10): 23651-67 Nephropedia Template TP {{tp|p=26445043|t=2015. Long Non-Coding RNAs as Master Regulators in Cardiovascular Diseases |pdf=|usr=}}{{26445043}} gab.com Text Long Non-Coding RNAs as Master Regulators in Cardiovascular Diseases JO: Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=26445043 #FOAvip Cardiovascular disease is the leading cause of death in the United States, accounting for nearly one in every seven deaths. Over the last decade, various targeted therapeutics have been introduced, but there has been no corresponding improvement in patient survival. Since the mortality rate of cardiovascular disease has not been significantly decreased, efforts have been made to understand the link between heart disease and novel therapeutic targets such as non-coding RNAs. Among multiple non-coding RNAs, long non-coding RNA (lncRNA) has emerged as a novel therapeutic in cardiovascular medicine. LncRNAs are endogenous RNAs that contain over 200 nucleotides and regulate gene expression. Recent studies suggest critical roles of lncRNAs in modulating the initiation and progression of cardiovascular diseases. For example, aberrant lncRNA expression has been associated with the pathogenesis of ischemic heart failure. In this article, we present a synopsis of recent discoveries that link the roles and molecular interactions of lncRNAs to cardiovascular diseases. Moreover, we describe the prevalence of circulating lncRNAs and assess their potential utilities as biomarkers for diagnosis and prognosis of heart disease. Twit Text FOAVip Long Non-Coding RNAs as Master Regulators in Cardiovascular Diseases ????Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=26445043 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26445043 #FOAvip English Wikipedia <ref>{{Cite pmid|26445043}}</ref> Long Non-Coding RNAs as Master Regulators in Cardiovascular Diseases #MMPMID26445043 Archer K; Broskova Z; Bayoumi AS; Teoh Jp; Davila A; Tang Y; Su H; Kim Im Int J Mol Sci 2015[Oct]; 16 (10): 23651-67 PMID26445043show ga Cardiovascular disease is the leading cause of death in the United States, accounting for nearly one in every seven deaths. Over the last decade, various targeted therapeutics have been introduced, but there has been no corresponding improvement in patient survival. Since the mortality rate of cardiovascular disease has not been significantly decreased, efforts have been made to understand the link between heart disease and novel therapeutic targets such as non-coding RNAs. Among multiple non-coding RNAs, long non-coding RNA (lncRNA) has emerged as a novel therapeutic in cardiovascular medicine. LncRNAs are endogenous RNAs that contain over 200 nucleotides and regulate gene expression. Recent studies suggest critical roles of lncRNAs in modulating the initiation and progression of cardiovascular diseases. For example, aberrant lncRNA expression has been associated with the pathogenesis of ischemic heart failure. In this article, we present a synopsis of recent discoveries that link the roles and molecular interactions of lncRNAs to cardiovascular diseases. Moreover, we describe the prevalence of circulating lncRNAs and assess their potential utilities as biomarkers for diagnosis and prognosis of heart disease. äLong Non-Coding RNAs as Master Regulators in Cardiovascular Diseases (epmc).pdf DeepDyve Pubget Overpricing