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10.1101/cshperspect.a016410 http://scihub22266oqcxt.onion/10.1101/cshperspect.a016410 C4632670!4632670!26525148     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cold+Spring+Harb+Perspect+Biol 2015 ; 7 (11): ä Nephropedia Template TP {{tp|p=26525148|t=2015. An Overview of the Molecular Mechanisms of Recombinational DNA Repair |pdf=|usr=}}{{26525148}} gab.com Text An Overview of the Molecular Mechanisms of Recombinational DNA Repair JO: Cold Spring Harb Perspect Biol http://www.kidney.de/pget.php?&tw=1&pmid=26525148 #FOAvip Recombinational DNA repair is a universal aspect of DNA metabolism and is essential for genomic integrity. It is a template-directed process that uses a second chromosomal copy (sister, daughter, or homolog) to ensure proper repair of broken chromosomes. The key steps of recombination are conserved from phage through human, and an overview of those steps is provided in this review. The first step is resection by helicases and nucleases to produce single-stranded DNA (ssDNA) that defines the homologous locus. The ssDNA is a scaffold for assembly of the RecA/RAD51 filament, which promotes the homology search. On finding homology, the nucleoprotein filament catalyzes exchange of DNA strands to form a joint molecule. Recombination is controlled by regulating the fate of both RecA/RAD51 filaments and DNA pairing intermediates. Finally, intermediates that mature into Holliday structures are disjoined by either nucleolytic resolution or topological dissolution. Twit Text FOAVip An Overview of the Molecular Mechanisms of Recombinational DNA Repair ????Cold Spring Harb Perspect Biol http://www.kidney.de/pget.php?&tw=1&pmid=26525148 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26525148 #FOAvip English Wikipedia <ref>{{Cite pmid|26525148}}</ref> An Overview of the Molecular Mechanisms of Recombinational DNA Repair #MMPMID26525148 Kowalczykowski SC Cold Spring Harb Perspect Biol 2015[Nov]; 7 (11): ä PMID26525148show ga Recombinational DNA repair is a universal aspect of DNA metabolism and is essential for genomic integrity. It is a template-directed process that uses a second chromosomal copy (sister, daughter, or homolog) to ensure proper repair of broken chromosomes. The key steps of recombination are conserved from phage through human, and an overview of those steps is provided in this review. The first step is resection by helicases and nucleases to produce single-stranded DNA (ssDNA) that defines the homologous locus. The ssDNA is a scaffold for assembly of the RecA/RAD51 filament, which promotes the homology search. On finding homology, the nucleoprotein filament catalyzes exchange of DNA strands to form a joint molecule. Recombination is controlled by regulating the fate of both RecA/RAD51 filaments and DNA pairing intermediates. Finally, intermediates that mature into Holliday structures are disjoined by either nucleolytic resolution or topological dissolution. äAn Overview of the Molecular Mechanisms of Recombinational DNA Repair (epmc).pdf DeepDyve Pubget Overpricing