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10.2183/pjab.91.292 http://scihub22266oqcxt.onion/10.2183/pjab.91.292 C4631895!4631895!26194854     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Proc+Jpn+Acad+Ser+B+Phys+Biol+Sci 2015 ; 91 (7): 292-304 Nephropedia Template TP {{tp|p=26194854|t=2015. Discovery of NKT cells and development of NKT cell-targeted anti-tumor immunotherapy |pdf=|usr=}}{{26194854}} gab.com Text Discovery of NKT cells and development of NKT cell-targeted anti-tumor immunotherapy JO: Proc Jpn Acad Ser B Phys Biol Sci http://www.kidney.de/pget.php?&tw=1&pmid=26194854 #FOAvip Natural Killer T (NKT) cells are unique lymphocytes characterized by their expression of a single invariant antigen receptor encoded by V?14J?18 in mice and V?24J?18 in humans, which recognizes glycolipid antigens in association with the monomorphic CD1d molecule. NKT cells mediate adjuvant activity to activate both CD8T cells to kill MHC-positive tumor cells and NK cells to eliminate MHC-negative tumor at the same time in patients, resulting in the complete eradication of tumors without relapse. Therefore, the NKT cell-targeted therapy can be applied to any type of tumor and also to anyone individual, regardless of HLA type.Phase IIa clinical trials on advanced lung cancers and head and neck tumors have been completed and showed significantly prolonged median survival times with only the primary treatment. Another potential treatment option for the future is to use induced pluripotent stem cell (iPS)-derived NKT cells, which induced adjuvant effects on anti-tumor responses, inhibiting in vivo tumor growth in a mouse model. Twit Text FOAVip Discovery of NKT cells and development of NKT cell-targeted anti-tumor immunotherapy ????Proc Jpn Acad Ser B Phys Biol Sci http://www.kidney.de/pget.php?&tw=1&pmid=26194854 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26194854 #FOAvip English Wikipedia <ref>{{Cite pmid|26194854}}</ref> Discovery of NKT cells and development of NKT cell-targeted anti-tumor immunotherapy #MMPMID26194854 TANIGUCHI M; HARADA M; DASHTSOODOL N; KOJO S Proc Jpn Acad Ser B Phys Biol Sci 2015[Jul]; 91 (7): 292-304 PMID26194854show ga Natural Killer T (NKT) cells are unique lymphocytes characterized by their expression of a single invariant antigen receptor encoded by V?14J?18 in mice and V?24J?18 in humans, which recognizes glycolipid antigens in association with the monomorphic CD1d molecule. NKT cells mediate adjuvant activity to activate both CD8T cells to kill MHC-positive tumor cells and NK cells to eliminate MHC-negative tumor at the same time in patients, resulting in the complete eradication of tumors without relapse. Therefore, the NKT cell-targeted therapy can be applied to any type of tumor and also to anyone individual, regardless of HLA type.Phase IIa clinical trials on advanced lung cancers and head and neck tumors have been completed and showed significantly prolonged median survival times with only the primary treatment. Another potential treatment option for the future is to use induced pluripotent stem cell (iPS)-derived NKT cells, which induced adjuvant effects on anti-tumor responses, inhibiting in vivo tumor growth in a mouse model. äDiscovery of NKT cells and development of NKT cell-targeted anti-tumor(epmc).pdf DeepDyve Pubget Overpricing