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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Geburtshilfe+Frauenheilkd
2015 ; 75
(10
): 1021-1027
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Statement by the Kommission Ovar of the AGO: The New FIGO and WHO Classifications
of Ovarian, Fallopian Tube and Primary Peritoneal Cancer
#MMPMID26556905
Meinhold-Heerlein I
; Fotopoulou C
; Harter P
; Kurzeder C
; Mustea A
; Wimberger P
; Hauptmann S
; Sehouli J
Geburtshilfe Frauenheilkd
2015[Oct]; 75
(10
): 1021-1027
PMID26556905
show ga
More than 25 years after the last revision, in 2012 the FIGO Oncology Committee
began revising the FIGO classification for staging ovarian, Fallopian tube and
primary peritoneal cancers. The new classification has become effective with its
publication at the beginning of 2014. Following recent findings on the
pathogenesis of ovarian, Fallopian tube and primary peritoneal cancer and
reflecting standard clinical practice, the three entities have now been
classified uniformly. The histological subtype is included (high-grade serous -
HGSC; low-grade serous - LGSC; mucinous - MC; clear cell - CCC; endometrioid -
EC). Stages III and IV have been fundamentally changed: stage IIIA now refers to
a localized tumor limited to the pelvis with (only) retroperitoneal lymph node
metastasis (formerly classified as IIIC). Stage IV has been divided into IVA and
IVB, with IVA defined as malignant pleural effusion and IVB as parenchymatous or
extra-abdominal metastasis including inguinal and mediastinal lymph node
metastasis as well as umbilical metastasis. A new WHO classification was
published almost concurrently. The classification of serous tumors addresses the
issue of the tubal carcinogenesis of serous ovarian cancer, even if no tubal
precursor lesions are found for up to 30?% of serous high-grade cancers. The
number of subgroups was reduced and subgroups now include only high-grade serous,
low-grade serous, mucinous, seromucinous, endometrioid, clear cell and Brenner
tumors. The category "transitional cell carcinomas" has been dropped and the
classification "seromucinous tumors" has been newly added. More attention has
been focused on the role of borderline tumors as a stage in the progression from
benign to invasive lesions.