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10.1152/ajpcell.00204.2015 http://scihub22266oqcxt.onion/10.1152/ajpcell.00204.2015 C4628938!4628938 !26354751     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26354751 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Am+J+Physiol+Cell+Physiol 2015 ; 309 (9 ): C580-9 Nephropedia Template TP {{tp|p=26354751 |t=2015. Hypoxia-inducible factors in T lymphocyte differentiation and function A Review in the Theme: Cellular Responses to Hypoxia |pdf=|usr=}}{{26354751 }} gab.com Text Hypoxia-inducible factors in T lymphocyte differentiation and function A Review in the Theme: Cellular Responses to Hypoxia JO: Am J Physiol Cell Physiol http://www.kidney.de/pget.php?&tw=1&pmid=26354751 #FOAvip Low oxygen concentrations or hypoxia is a trait common to inflamed tissues. Therefore it is not surprising that pathways of hypoxic stress response, largely governed by hypoxia-inducible factors (HIF), are highly relevant to the proper function of immune cells. HIF expression and stabilization in immune cells can be triggered not only by hypoxia, but also by a variety of stimuli and pathological stresses associated with leukocyte activation and inflammation. In addition to its role as a sensor of oxygen scarcity, HIF is also a major regulator of immune cell metabolic function. Rapid progress is being made in elucidating the roles played by HIF in diverse aspects of both innate and adaptive immunity. Here we discuss a number of breakthroughs that have shed light on how HIF expression and activity impact the differentiation and function of diverse T cell populations. The insights gained from these findings may serve as the foundation for future therapies aimed at fine-tuning the immune response. Twit Text FOAVip Hypoxia-inducible factors in T lymphocyte differentiation and function A Review in the Theme: Cellular Responses to Hypoxia ????Am J Physiol Cell Physiol http://www.kidney.de/pget.php?&tw=1&pmid=26354751 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26354751 #FOAvip English Wikipedia <ref>{{Cite pmid|26354751 }}</ref> Hypoxia-inducible factors in T lymphocyte differentiation and function A Review in the Theme: Cellular Responses to Hypoxia #MMPMID26354751 Tao JH ; Barbi J ; Pan F Am J Physiol Cell Physiol 2015[Nov]; 309 (9 ): C580-9 PMID26354751 show ga Low oxygen concentrations or hypoxia is a trait common to inflamed tissues. Therefore it is not surprising that pathways of hypoxic stress response, largely governed by hypoxia-inducible factors (HIF), are highly relevant to the proper function of immune cells. HIF expression and stabilization in immune cells can be triggered not only by hypoxia, but also by a variety of stimuli and pathological stresses associated with leukocyte activation and inflammation. In addition to its role as a sensor of oxygen scarcity, HIF is also a major regulator of immune cell metabolic function. Rapid progress is being made in elucidating the roles played by HIF in diverse aspects of both innate and adaptive immunity. Here we discuss a number of breakthroughs that have shed light on how HIF expression and activity impact the differentiation and function of diverse T cell populations. The insights gained from these findings may serve as the foundation for future therapies aimed at fine-tuning the immune response. |*Cell Differentiation [MESH] |*Lymphocyte Activation [MESH] |Animals [MESH] |CD8-Positive T-Lymphocytes/immunology/metabolism [MESH] |Cell Hypoxia [MESH] |Humans [MESH] |Hypoxia-Inducible Factor 1/immunology/*metabolism [MESH] |Hypoxia/immunology/*metabolism [MESH] |Oxygen/immunology/*metabolism [MESH] |Signal Transduction [MESH] |T-Lymphocyte Subsets/immunology/*metabolism [MESH]Hypoxia-inducible factors in T lymphocyte differentiation and function(epmc).pdf DeepDyve Pubget Overpricing