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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Br+J+Radiol
2015 ; 88
(1049
): 20150025
Nephropedia Template TP
gab.com Text
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English Wikipedia
Cardiac MR enables diagnosis in 90% of patients with acute chest pain, elevated
biomarkers and unobstructed coronary arteries
#MMPMID25782462
Emrich T
; Emrich K
; Abegunewardene N
; Oberholzer K
; Dueber C
; Muenzel T
; Kreitner KF
Br J Radiol
2015[May]; 88
(1049
): 20150025
PMID25782462
show ga
OBJECTIVE: To assess the diagnostic value of cardiac MRI (CMR) in patients with
acute chest pain, elevated cardiac enzymes and a negative coronary angiogram.
METHODS: This study included a total of 125 patients treated in the chest pain
unit during a 39-month period. Each included patient underwent MRI within a
median of 3 days after cardiac catheterization. The MRI protocol comprised cine,
oedema-sensitive and late gadolinium-enhancement imaging. The standard of
reference was a consensus diagnosis based on clinical follow-up and the synopsis
of all clinical, laboratory and imaging data. RESULTS: MRI revealed a multitude
of diagnoses, including ischaemic cardiomyopathy (CM), dilated CM, myocarditis,
Takotsubo CM, hypertensive heart disease, hypertrophic CM, cardiac amyloidosis
and non-compaction CM. MRI-based diagnoses were the same as the final reference
diagnoses in 113/125 patients (90%), with the two diagnoses differing in only
12/125 patients. In two patients, no final diagnosis could be established.
CONCLUSION: CMR performed early after the onset of symptoms revealed a broad
spectrum of diseases. CMR delivered a correct final diagnosis in 90% of patients
with acute chest pain, elevated cardiac enzymes and a negative coronary
angiogram. ADVANCES IN KNOWLEDGE: Diagnosing patients with acute coronary
syndrome but unobstructed coronary arteries remains a challenge for
cardiologists. CMR performed early after catheterization reveals a broad spectrum
of diseases with only a simple and quick examination protocol, and there is a
high concordance between MRI-based diagnoses and final reference diagnoses.