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10.1259/bjr.20150025

http://scihub22266oqcxt.onion/10.1259/bjr.20150025
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suck abstract from ncbi


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pmid25782462
      Br+J+Radiol 2015 ; 88 (1049 ): 20150025
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  • Cardiac MR enables diagnosis in 90% of patients with acute chest pain, elevated biomarkers and unobstructed coronary arteries #MMPMID25782462
  • Emrich T ; Emrich K ; Abegunewardene N ; Oberholzer K ; Dueber C ; Muenzel T ; Kreitner KF
  • Br J Radiol 2015[May]; 88 (1049 ): 20150025 PMID25782462 show ga
  • OBJECTIVE: To assess the diagnostic value of cardiac MRI (CMR) in patients with acute chest pain, elevated cardiac enzymes and a negative coronary angiogram. METHODS: This study included a total of 125 patients treated in the chest pain unit during a 39-month period. Each included patient underwent MRI within a median of 3 days after cardiac catheterization. The MRI protocol comprised cine, oedema-sensitive and late gadolinium-enhancement imaging. The standard of reference was a consensus diagnosis based on clinical follow-up and the synopsis of all clinical, laboratory and imaging data. RESULTS: MRI revealed a multitude of diagnoses, including ischaemic cardiomyopathy (CM), dilated CM, myocarditis, Takotsubo CM, hypertensive heart disease, hypertrophic CM, cardiac amyloidosis and non-compaction CM. MRI-based diagnoses were the same as the final reference diagnoses in 113/125 patients (90%), with the two diagnoses differing in only 12/125 patients. In two patients, no final diagnosis could be established. CONCLUSION: CMR performed early after the onset of symptoms revealed a broad spectrum of diseases. CMR delivered a correct final diagnosis in 90% of patients with acute chest pain, elevated cardiac enzymes and a negative coronary angiogram. ADVANCES IN KNOWLEDGE: Diagnosing patients with acute coronary syndrome but unobstructed coronary arteries remains a challenge for cardiologists. CMR performed early after catheterization reveals a broad spectrum of diseases with only a simple and quick examination protocol, and there is a high concordance between MRI-based diagnoses and final reference diagnoses.
  • |Adult [MESH]
  • |Aged [MESH]
  • |Aged, 80 and over [MESH]
  • |Biomarkers/blood [MESH]
  • |Cardiac Catheterization [MESH]
  • |Cardiovascular Diseases/*diagnosis/enzymology [MESH]
  • |Chest Pain/diagnosis/enzymology [MESH]
  • |Contrast Media [MESH]
  • |Coronary Angiography [MESH]
  • |Female [MESH]
  • |Gadolinium DTPA [MESH]
  • |Humans [MESH]
  • |Magnetic Resonance Imaging, Cine/*methods [MESH]
  • |Male [MESH]
  • |Middle Aged [MESH]
  • |Predictive Value of Tests [MESH]
  • |Risk Assessment [MESH]


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