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2015 ; 33
(2
): 77-82
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Best practices for controlled ovarian stimulation in in vitro fertilization
#MMPMID25734345
Jungheim ES
; Meyer MF
; Broughton DE
Semin Reprod Med
2015[Mar]; 33
(2
): 77-82
PMID25734345
show ga
As applications for IVF have expanded over the years, so too have approaches to
controlled ovarian stimulation (COS) for IVF. With this expansion and improved
knowledge of basic reproductive biology, there is increasing interest in how COS
practice influences IVF outcomes, and whether or not specific treatment scenarios
call for personalized approaches to COS. For the majority of women undergoing COS
and their treating physicians, the goal is to achieve a healthy live birth
through IVF in a fresh cycle. Opinions on how COS strategy best leads to this
common goal varies among centers as many clinicians base COS strategy not on
evidence obtained through prospective randomized trials, but rather through
observational studies and experience. Overall, when it comes to COS most
clinicians recognize the approach should not be "one size fits all," but rather a
patient-centered approach that takes the existing evidence into consideration. We
outline the existing evidence for best practices in COS for IVF, highlighting how
these practices may be incorporated into a patient-centered approach.
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