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10.1016/j.sjbs.2015.03.005 http://scihub22266oqcxt.onion/10.1016/j.sjbs.2015.03.005 C4625378!4625378!26587005     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Saudi+J+Biol+Sci 2015 ; 22 (6): 760-72 Nephropedia Template TP {{tp|p=26587005|t=2015. Regulation of ceramide channel formation and disassembly: Insights on the initiation of apoptosis |pdf=|usr=}}{{26587005}} gab.com Text Regulation of ceramide channel formation and disassembly: Insights on the initiation of apoptosis JO: Saudi J Biol Sci http://www.kidney.de/pget.php?&tw=1&pmid=26587005 #FOAvip Sphingolipid research has surged in the past two decades and has produced a wide variety of evidence supporting the role of this class of molecules in mediating cellular growth, differentiation, senescence, and apoptosis. Ceramides are a subgroup of sphingolipids (SLs) that are directly involved in the process of initiation of apoptosis. We, and others, have recently shown that ceramides are capable of the formation of protein-permeable channels in mitochondrial outer membranes under physiological conditions. These pores are indeed good candidates for the pathway of release of pro-apoptotic proteins from the mitochondrial intermembrane space (IMS) into the cytosol to initiate intrinsic apoptosis. Here, we review recent findings on the regulation of ceramide channel formation and disassembly, highlighting possible implications on the initiation of the intrinsic apoptotic pathway. Twit Text FOAVip Regulation of ceramide channel formation and disassembly: Insights on the initiation of apoptosis ????Saudi J Biol Sci http://www.kidney.de/pget.php?&tw=1&pmid=26587005 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26587005 #FOAvip English Wikipedia <ref>{{Cite pmid|26587005}}</ref> Regulation of ceramide channel formation and disassembly: Insights on the initiation of apoptosis #MMPMID26587005 Abou-Ghali M; Stiban J Saudi J Biol Sci 2015[Nov]; 22 (6): 760-72 PMID26587005show ga Sphingolipid research has surged in the past two decades and has produced a wide variety of evidence supporting the role of this class of molecules in mediating cellular growth, differentiation, senescence, and apoptosis. Ceramides are a subgroup of sphingolipids (SLs) that are directly involved in the process of initiation of apoptosis. We, and others, have recently shown that ceramides are capable of the formation of protein-permeable channels in mitochondrial outer membranes under physiological conditions. These pores are indeed good candidates for the pathway of release of pro-apoptotic proteins from the mitochondrial intermembrane space (IMS) into the cytosol to initiate intrinsic apoptosis. Here, we review recent findings on the regulation of ceramide channel formation and disassembly, highlighting possible implications on the initiation of the intrinsic apoptotic pathway. äRegulation of ceramide channel formation and disassembly: Insights on (epmc).pdf DeepDyve Pubget Overpricing